Mohan B. Krishnamurthy

Prospective randomised trial comparing thermal ablation With laparoscopic Adrenalectomy as an alternatiVE treatment for unilateral asymmetric primary aldosteronism: a protocol for the WAVE trial

Kate Laycock, Jessica Kearney, Yun-Ni Lee, James MacFarlane et autres

INTRODUCTION: Unilateral aldosterone-producing adenomas (>1 cm) and aldosterone-producing nodules (<1 cm) are a common cause of primary aldosteronism (PA) and hypertension. Adrenal surgery can potentially cure or significantly improve the condition. However, fewer than 1% of patients with PA undergo adrenalectomy. For …

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SUN-243 Micronodular Asymmetrical Disease and Lack of Rigorous Biochemical Success following Adrenalectomy for Primary Aldosteronism detected by PET-CT Imaging and Post-Operative Confirmatory Testing

Jessica Kearney, Daniel Gillett, Emily Goodchild, Heok Cheow et autres

Abstract Disclosure: J. Kearney: None. D. Gillett: None. E. Goodchild: None. H. Cheow: None. M. Krishnamurthy: None. K. Laycock: None. X. Wu: None. M. Gurnell: None. W. Drake: None. M.J. Brown: None. Background: Complete clinical success, defined by PASO criteria, is achieved …

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Can voxel analysis of [11C]Metomidate PETCT be used to detect micronodular disease and predict outcome from adrenalectomy?

Jessica Kearney, Daniel Gillett, Bal Sanghera, Heok Cheow et autres

Reducing severe intraventricular haemorrhage rates in <26‐week preterm infants with bedside assessment and care bundle implementation

Simone Huntingford, Lindsay Zhou, Catherine Fox, Taryn Miller et autres

AIM: To assess staff adherence to a 'Preterm Brain Injury Prevention Bundle', and its effectiveness in reducing severe intraventricular haemorrhage (IVH) rates and risk factors in extremely preterm infants born at <26 weeks' gestation. METHODS: Adherence to the bundle was assessed using …

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Ultrasound Measurements of Intracranial Structures in Growth-Restricted Neonates with Fetal Blood Flow Redistribution: A Pilot Observational Study

Pramod Pharande, Mohan B. Krishnamurthy, Gillian Whiteley, Arun Sasi et autres

BACKGROUND: Fetal growth restriction (FGR) is associated with neonatal and long-term neuro-morbidity. Preferential redistribution of blood flow to the brain is a common antenatal adaptation in FGR. The impact of this "brain sparing," which may signify severity of FGR, on the growth …

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Toward rational management of patent ductus arteriosus: ductal disease staging and first line paracetamol

Arvind Sehgal, Itamar Nitzan, Mohan B. Krishnamurthy, Pramod Pharande et autres

Aims To study paracetamol (PCM) use as first line therapy for significant patent ductus arteriosus (sPDA) closure, stratified by echocardiography.Methods In this retrospective observational study, a prepublished score comprising PDA size and velocity, PDA:left pulmonary artery ratio, diastolic flow in main and …

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Neonatal alloimmune neutropaenia: Experience from an Australian paediatric health service

John Doan, Kottayam Radhakrishnan, Mohan B. Krishnamurthy, Anil K. Malhotra

Aim To describe the presenting features and investigation findings in infants diagnosed with neonatal alloimmune neutropaenia (NAIN) within an Australian paediatric health network. The secondary aim was to describe the management and resolution of neutropaenia in infants with NAIN. Methods A retrospective …

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Postnatal middle cerebral artery Dopplers in growth-restricted neonates

Mohan B. Krishnamurthy, Pramod Pharande, Gillian Whiteley, Ryan Hodges et autres

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ACE inhibition for severe bronchopulmonary dysplasia - an approach based on physiology

Arvind Sehgal, Mohan B. Krishnamurthy, Megan Clark, Samuel Menahem

Premature infants have a high incidence of bronchopulmonary dysplasia (BPD). Systemic hypertension, arterial thickness and stiffness, and increased systemic afterload may all contribute to BPD pathophysiology by altering left ventricular (LV) function and increasing pulmonary venous congestion by lowering end-diastolic compliance. This …

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Octreotide Use in Neonates: A Case Series

Syed Ahmed Zaki, Mohan B. Krishnamurthy, Anil K. Malhotra

BACKGROUND AND OBJECTIVE: Octreotide is a somatostatin analogue and has been used off-label for a variety of conditions. There are no specific guidelines for the use of octreotide in neonates and its safety and efficacy have not been systematically evaluated. The objective …

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Congenital chylothorax: current perspectives and trends

Mohan B. Krishnamurthy, Anil K. Malhotra

Abstract: Congenital chylothorax (CC) is the most common cause of pleural effusion in the perinatal period. The etiology is unknown in the majority of the cases. However, in some cases, it can be associated with various syndromes and genetic conditions. CC is …

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Screening investigations in small-for-gestational-age near-term and term infants

Mohan B. Krishnamurthy, Abigail Popiel, Anil K. Malhotra

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