Daniele Nicolis

Temperature control optimization in insulin pumps for the prevention of insulin denaturation

Jasmine Rosselli, Michael Kradolfer, Nadia Möri, J Stucki et autres

Modern diabetes care increasingly relies on insulin pumps for continuous subcutaneous delivery. Because insulin is highly temperature-sensitive, it must be maintained between 2 °C and30 °C to preserve its structural integrity and therapeutic efficacy. Exposure to temperatures outside this window causes protein …

Role of Atrial Pacing Support in Cardiac Resynchronization Therapy: A Noninferiority Randomized Trial

M Biffi, Giovanni Rovaris, Ennio Carmine Luigi Pisanò, Calvi et autres

BACKGROUND: The role of atrial pacing support is unclear in patients receiving cardiac resynchronization therapy–defibrillator (CRT-D) without sinus node dysfunction. METHODS: We conducted a randomized, parallel-group, noninferiority trial to evaluate whether a 2-lead CRT-D capable of atrial sensing (but no pacing) by …

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Is there an association between device-detected atrial fibrillation and diabetes? A propensity score-matched analysis from the Italian Home Monitoring Expert Alliance project

Giovanni Malanchini, Eduardo Celentano, Antonio Curnis, Giovanni Rovaris et autres

Abstract Background Device-detected atrial fibrillation (DDAF) is frequently observed in patients with cardiac implantable devices that allow continuous atrial rhythm monitoring. While some previous studies have found a significant association between clinical atrial fibrillation and diabetes, the relationship between DDAF and diabetes …

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Association between device-detected subclinical atrial fibrillation and diabetes in patients with implantable cardioverter-defibrillators: A propensity score-matched analysis

Giovanni Malanchini, Eduardo Celentano, Antonio Curnis, Giovanni Rovaris et autres

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Subcutaneous Implantable Defibrillators in Young Patients: Arrhythmias, Complications, and Physical Activity

Pietro Francia, Matteo Ziacchi, Federico Migliore, Paolo De Filippo et autres

BACKGROUND: The safety of subcutaneous implantable cardioverter defibrillator (S-ICD) recipients who lead active lifestyles and engage in recreational sports is unknown. We aimed to evaluate the association between lifestyle and recreational sports and the occurrence of arrhythmia- and device-related complications, appropriate and …

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PO-01-108 NOVEL CRYO-BALLOON TECHNOLOGY FOR SUCCESSFUL ATRIAL FIBRILLATION ABLATION AND IMPACT OF PULMONARY VEIN VARIANT ANATOMY: COOLING CHARACTERISTICS AND 1-YEAR OUTCOME FROM THE CHARISMA REGISTRY

Pietro Rossi, Claudio Tondo, Saverio Iacopino, Massimo Moltrasio et autres

Impact of pulmonary vein variant anatomy during cryo-ablation in paroxysmal and persistent AF patients: 1-year outcome from a nationwide multicenter clinical setting

Massimo Moltrasio, Stefano Bianchi, Saverio Iacopino, Claudio Tondo et autres

Abstract Background Complete electrical pulmonary vein isolation (PVI) by cryo-balloon approach is a well-established ablation strategy of atrial fibrillation (AF). While contrast findings exist regarding the influence of variant pulmonary vein (PV) anatomy on predicting AF recurrence, limited data are currently available …

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High‐density mapping of Koch's triangle during sinus rhythm and typical atrioventricular nodal re‐entrant tachycardia, integrated with direct recording of atrio‐ventricular node structure potential

Claudio Pandozi, Giovanni Luca Botto, Maria Luisa Loricchio, Matteo D'Ammando et autres

BACKGROUND: The mechanism of typical slow-fast atrioventricular nodal re-entrant tachycardia (AVNRT) and its anatomical and electrophysiological circuit inside the right atrium (RA) and Koch's Triangle (KT) are not well known. OBJECTIVE: To identify the potentials of the compact AV node and inferior …

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Timing of cryoballoon pulmonary vein isolation to prevent atrial fibrillation recurrence

Giuseppe Stabile, Roberto Verlato, Giuseppe Arena, Paolo Pieragnoli et autres

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P102 DIFFERENCES IN HIGH–DENSITY MAPPING OF KOCH‘S TRIANGLE DURING TYPICAL AV NODAL REENTRANT TACHYCARDIA INTEGRATED AND NOT INTEGRATED WITH DIRECT RECORDING OF ATRIOVENTRICULAR NODE STRUCTURES POTENTIAL: A MULTICENTER NON–RANDOMIZED STUDY

Andrea Matteucci, Marco Galeazzi, Maurizio Russo, Giovanni Luca Botto et autres

Abstract Background Despite the sustained efforts and advances in the fields of anatomy, histology, immunohistochemistry and cardiac mapping, the definition of the AVNRT circuit in humans is still incomplete. This discouraging result can be explained by many reasons, but the most important …

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P101 HIGH–DENSITY MAPPING OF KOCH‘S TRIANGLE DURING SINUS RHYTHM AND TYPICAL AV NODAL REENTRANT TACHYCARDIA INTEGRATED WITH THE DIRECT RECORDING OF ATRIOVENTRICULAR NODE STRUCTURES POTENTIAL: A MULTICENTER NON–RANDOMIZED STUDY

Andrea Matteucci, Maurizio Russo, Marco Galeazzi, Giovanni Luca Botto et autres

Abstract Background Atrioventricular nodal re–entrant tachycardia (AVNRT) is humans‘ most frequent regular tachycardia. Nevertheless, understanding the exact mechanism and pathways involved in the circuit that sustains the arrhythmia is still incomplete. Also, the recording of nodal potential was performed previously in animals …

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A DNA biosensors-based microfluidic platform for attomolar real-time detection of unamplified SARS-CoV-2 virus

Perrine Robin, Laura Barnabei, Stefano Marocco, Jacopo Pagnoncelli et autres

The emergence of the coronavirus 2019 (COVID-19) arose the need for rapid, accurate and massive virus detection methods to control the spread of infectious diseases. In this work, a device, deployable in non-medical environments, has been developed for the detection of non-amplified …

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