Genome-scale CRISPR screens identify PTGES3 as a direct modulator of androgen receptor function in advanced prostate cancer
Haolong Li, James E. Melnyk, Becky Xu Hua Fu, Raunak Shrestha et autres
7 citationsNature Genetics
James E. Melnyk
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22Publications signalées
7007Citations signalées
1Affiliations récentes
Institutions déclarées
Domaines associés
Immune Response and InflammationSARS-CoV-2 and COVID-19 ResearchProstate Cancer Treatment and ResearchGut microbiota and healthComputational Drug Discovery Methods
Publications récentes
Genome-wide CRISPR screens identify PTGES3 as a novel AR modulator
Haolong Li, James E. Melnyk, Becky Xu Hua Fu, Raunak Shrestha et autres
0 citationsbioRxiv (Cold Spring Harbor Laboratory)
Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets
Kelsey M. Haas, Michael McGregor, Mehdi Bouhaddou, Benjamin J. Polacco et autres
68 citationsNature Communications
Abstract B066: Genome-wide CRISPR screens identify PTGES3 as a druggable AR modulator
Haolong Li, James E. Melnyk, Becky Xu Hua Fu, Siyu Feng et autres
1 citationCancer Research
Targeting a splicing-mediated drug resistance mechanism in prostate cancer by inhibiting transcriptional regulation by PKCβ1
James E. Melnyk, Veronica Steri, Hao G. Nguyen, Yeonjoo Hwang et autres
17 citationsOncogene
Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant
Ann‐Kathrin Reuschl, Lucy Thorne, Lorena Zuliani‐Alvarez, Mehdi Bouhaddou et autres
42 citationsbioRxiv (Cold Spring Harbor Laboratory)
The splicing modulator sulfonamide indisulam reduces AR-V7 in prostate cancer cells
James E. Melnyk, Veronica Steri, Hao G. Nguyen, Byron Hann et autres
47 citationsBioorganic & Medicinal Chemistry
The Global Phosphorylation Landscape of SARS-CoV-2 Infection
Mehdi Bouhaddou, Danish Memon, Bjoern Meyer, Kris M. White et autres
1159 citationsCell
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
Christoper Mathy, Robert M. Stroud, Kevin Lou, Jiewei Xu et autres
3 citationsCarolina Digital Repository (University of North Carolina at Chapel Hill)
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
David E. Gordon, Gwendolyn Μ. Jang, Mehdi Bouhaddou, Jiewei Xu et autres
4898 citationsNature
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
David E. Gordon, Gwendolyn Μ. Jang, Mehdi Bouhaddou, Jiewei Xu et autres
456 citationsbioRxiv (Cold Spring Harbor Laboratory)
Pathogen- and Microbial- Associated Molecular Patterns (PAMPs/MAMPs) and the Innate Immune Response in Crohn’s Disease
Amy K. Schaefer, James E. Melnyk, Zhaoping He, J. Fernando del Rosario et autres
20 citationsElsevier eBooks
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