109 Functional activity, but not PD-1 expression level, differentiates primary CLL from healthy PD1+ T cells using SCNP
Shujing Liang, Lok Wa Laura Leung, Sanjana Putta, Drew Hotson et autres
1 citation
European Journal of Cancer
Drew Hotson
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3Publications signalées
14Citations signalées
1Affiliations récentes
Les institutions déclarées
Les domaines associés
Cancer Immunotherapy and BiomarkersCAR-T cell therapy researchMelanoma and MAPK PathwaysImmune Cell Function and InteractionChronic Lymphocytic Leukemia Research
Les publications récentes
Systems biology analysis of immune signaling in peripheral blood mononuclear cells (PBMC) of melanoma patients receiving ipilimumab; basis for response biomarker identification
Drew Hotson, Ryan Alvarado, Andy Conroy, Santosh Putta et autres
Ipilimumab, an anti-CTLA-4 monoclonal antibody, is approved for treatment of unresectable/metastatic melanoma [ 1 ]. Treatment benefits only a subset of patients (pts) and is associated with significant adverse effects. Biomarkers of pt response are needed. Single cell network profiling (SCNP) is …
us, it (code pays fourni par la source)
12 citations
Journal of Translational Medicine
Systems biology analysis of immune signaling in peripheral blood mononuclear cells (PBMC) of melanoma patients receiving ipilimumab; basis for clinical response biomarker identification
Drew Hotson, Ryan Alvarado, Andrew Conroy, Santosh Putta et autres
Meeting abstracts Ipilimumab, an anti-CTLA-4 monoclonal antibody, is approved for treatment of unresectable/metastatic melanoma. Treatment benefits only a subset of patients (pts) and is associated with significant adverse effects. Biomarkers of pt response are needed. Single cell network profiling
us, it (code pays fourni par la source)
1 citation
Journal for ImmunoTherapy of Cancer
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