Dominik Rachoń

Time-Dependent Effects of PFAS and Their Mixtures on Ovarian Epithelial Cell Proliferation and Chemotherapeutic Response

Robinson Ajana, Dominik Rachoń, Grażyna Gałęzowska

Per- and polyfluoroalkyl substances (PFAS) are an emerging group of anthropogenic environmental pollutants frequently detected in human and animal serum. Although several studies have reported adverse health effects associated with exposure to single PFAS, limited information is available concerning the biological and …

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Reproductive toxicity of per- and polyfluoroalkyl substances

Robinson Ajana, Dominik Rachoń, Grażyna Gałęzowska

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Alteration of the tryptophan concentrations in women with polycystic ovary syndrome (PCOS)

Katarzyna Paczkowska, Dominik Rachoń, Andrzej Berg, Jacek Rybka et autres

Framework guidelines for the process of caring for the health of adolescent transgender (T) and non-binary (NB) people experiencing gender dysphoria — the position statement of the expert panel

Aneta Gawlik, Marta Dora, Dorota Baran, Łukasz Szostkiewicz et autres

This article presents framework guidelines for the care of adolescent transgender (T) and non-binary (NB) individuals experiencing gender dysphoria (GD) and/or gender incongruence (GI). Developed by a multidisciplinary expert panel, these guidelines aim to address the complex medical, psychological, and social needs …

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Depression, higher level of tension induction, and impaired coping strategies in response to stress in women with PCOS correlate with clinical and laboratory indices of hyperandrogenism and not with central obesity and insulin resistance

Edyta Dutkiewicz, Dominik Rachoń, Miłosz Dziedziak, Agnieszka Kowalewska et autres

PCOS is characterized by ovarian hyperandrogenism and insulin resistance (IR), which give rise to symptoms of hyperandrogenism and central obesity, which in turn may cause depression, lower self-esteem, and deteriorate coping strategies in stressful situations. THE PURPOSE: to examine the mental condition, …

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Determination of urinary androgens in women with polycystic ovary syndrome using LC-QqQ/MS and the application of thin film solid-phase microextraction (TF-SPME)

Anna Rajska, Joanna Raczak‐Gutknecht, Wiktoria Struck‐Lewicka, Magdalena Buszewska‐Forajta et autres

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Assessment of baby disposable diapers application for urine collection and determination of phthalate metabolites

Marta Glinka, Katarzyna Jażdżewska, Christina Vakh, Izabela Drążkowska et autres

The baby disposable diapers were investigated as a sampling material for urine collection and validated for the evaluation of the exposure of children to xenobiotics. Phthalate metabolites detected in urine samples were chosen as proof-of-concept analytes. For the determination of phthalate metabolites …

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Bisphenol A analogues and metabolic syndrome in women with polycystic ovary syndrome

Joanna Majewska, Andrzej Berg, Joanna Jurewicz, Katarzyna Owczarek et autres

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Alteration of Branched-Chain and Aromatic Amino Acid Profile as a Novel Approach in Studying Polycystic Ovary Syndrome Pathogenesis

Katarzyna Paczkowska, Dominik Rachoń, Andrzej Berg, Jacek Rybka et autres

Polycystic ovary syndrome (PCOS) is a common endocrine disorder that affects reproductive-age women and predisposes them to the development of metabolic disturbances. Recent research has shown that several metabolic factors may play a role in PCOS pathogenesis, and it has been suggested …

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Searching for the primary metabolic alterations of polycystic ovary syndrome by application of the untargeted metabolomics approach

Anna Rajska, Magdalena Buszewska‐Forajta, Szymon Macioszek, Renata Wawrzyniak et autres

Despite a large number of studies, the pathogenesis of polycystic ovary syndrome (PCOS) still remains unexplained. In light of ambiguous observations reported in metabolomics, there is a need to carry out studies focusing on confirming the discriminating power of the proposed metabolomics …

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Early markers of metabolic disorders, such as leucin and isoleucine level and lipid accumulation product, should be considered as the potential additional criterium in PCOS classification

Katarzyna Paczkowska, Dominik Rachoń, Andrzej Berg, Jacek Rybka et autres

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Alkohol i człowiek - toksyczny związek

Jacek Sein Anand, Marek Wiergowski, Witold Bachorski, Aleksandra Biedrzycka et autres

Książka pod redakcją naukową Jacka Sein Ananda oraz Marka Wiergowskiego „Alkohol i człowiek – toksyczny związek” to znakomita naukowa monografia o mechanizmach uzależnień. Czytelnik otrzymuje solidną porcję wiedzy podaną w sposób bardzo dobrze przyswajalny. Jednak nie tylko przekazana wiedza teoretyczna przesądza o …