Accès ouvert
2024
article
OpenAlex
Ilayda Ozsan McMillan, Li Liang, Guowei Su, Xuehong Song et autres
The triggering receptor expressed on myeloid cells-2 (TREM2), a pivotal innate immune receptor, orchestrates functions such as inflammatory responses, phagocytosis, cell survival, and neuroprotection. TREM2 variants R47H and R62H have been associated with Alzheimer's disease, yet the underlying mechanisms remain elusive. Our …
us
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Accès ouvert
2022
article
OpenAlex
Jicheng Zhang, Li Liang, Weizhun Yang, Sherif Ramadan et autres
Heparan sulfate (HS) plays important roles in many biological processes. The inherent complexity of naturally existing HS has severely hindered the thorough understanding of their structure-activity relationship. To facilitate biological studies, a new strategy has been developed to synthesize a HS-like pseudo-hexasaccharide …
us, Égypte
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Accès ouvert
2022
article
OpenAlex
Jicheng Zhang, Li Liang, Weizhun Yang, Sherif Ramadan et autres
Abstract Heparan sulfate (HS) plays important roles in many biological processes. The inherent complexity of naturally existing HS has severely hindered the thorough understanding of their structure‐activity relationship. To facilitate biological studies, a new strategy has been developed to synthesize a HS‐like …
us, Égypte
(code pays fourni par la source)
Accès ouvert
2022
preprint
OpenAlex
Jicheng Zhang, Li Liang, Weizhun Yang, Sherif Ramadan et autres
Heparan sulfate (HS) plays significant roles in various biological processes such as inflammation, cell proliferation, and bacterial and viral infection. The inherent complexity of naturally existing HS has severely hindered the thorough understanding of the relationship between their diverse structures and biological …
us
(code pays fourni par la source)
Accès ouvert
2022
preprint
OpenAlex
Jicheng Zhang, Li Liang, Weizhun Yang, Sherif Ramadan et autres
Heparan sulfate (HS) plays significant roles in various biological processes such as inflammation, cell proliferation, and bacterial and viral infection. The inherent complexity of naturally existing HS has severely hindered the thorough understanding of the relationship between their diverse structures and biological …
us
(code pays fourni par la source)