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Profil bibliographique

Alejandra Ancira-Cortez

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

17Publications signalées
176Citations signalées
1Affiliations récentes

Les institutions déclarées

Les domaines associés

Radiopharmaceutical Chemistry and ApplicationsNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsPeptidase Inhibition and AnalysisProstate Cancer Treatment and Research

Les publications récentes

Accès ouvert 2024 article OpenAlex

Molecularly Targeted Lanthanide Nanoparticles for Cancer Theranostic Applications

Guillermina Ferro‐Flores, Alejandra Ancira-Cortez, Blanca Ocampo‐García, Laura Meléndez‐Alafort

Injectable colloidal solutions of lanthanide oxides (nanoparticles between 10 and 100 nm in size) have demonstrated high biocompatibility and no toxicity when the nanoparticulate units are functionalized with specific biomolecules that molecularly target various proteins in the tumor microenvironment. Among the proteins …

mx, it (code pays fourni par la source)

26 citations Nanomaterials
Accès ouvert 2023 article OpenAlex

Improving Overall Survival and Quality of Life in Patients with Prostate Cancer and Neuroendocrine Tumors Using 177Lu-iPSMA and 177Lu-DOTATOC: Experience after 905 Treatment Doses

Myrna Luna‐Gutiérrez, Rodrigo Hernández-Ramírez, Airam Soto-Abundiz, Francisco O. García-Pérez et autres

177Lu-iPSMA is a novel radioligand developed at ININ-Mexico with a high affinity for the PSMA protein heavily expressed in cancer cells of approximately 95% of patients with metastatic castration-resistant prostate cancer (mCRPC). 177Lu-DOTATOC is a patent-free radioligand, molecularly recognized by somatostatin receptors …

mx (code pays fourni par la source)

9 citations Pharmaceutics
Accès ouvert 2023 article OpenAlex

Chemo-radiotherapy with 177Lu-PLGA(RGF)-CXCR4L for the targeted treatment of colorectal cancer

Pedro Cruz-Nova, Brenda Gibbens-Bandala, Alejandra Ancira-Cortez, Gerardo Ramírez-Nava et autres

Introduction More than 1.9 million new cases of colorectal cancer and 935,000 deaths were estimated to have occurred worldwide in 2020. Therapies for metastatic colorectal cancer include cytotoxic chemotherapy and targeted therapies in multiple lines of treatment. Nevertheless, the optimal use of …

mx (code pays fourni par la source)

8 citations Frontiers in Medicine
Accès ouvert 2022 article OpenAlex

Toxicity Assessment of [177Lu]Lu−iFAP/iPSMA Nanoparticles Prepared under GMP-Compliant Radiopharmaceutical Processes

Tania Hernández-Jiménez, Pedro Cruz-Nova, Alejandra Ancira-Cortez, Brenda Gibbens-Bandala et autres

The fibroblast activation protein (FAP) is heavily expressed in fibroblasts associated with the tumor microenvironment, while the prostate-specific membrane antigen (PSMA) is expressed in the neovasculature of malignant angiogenic processes. Previously, we reported that [177Lu]lutetium sesquioxide-iFAP/iPSMA nanoparticles ([177Lu]Lu−iFAP/iPSMA) inhibit HCT116 tumor progression …

mx (code pays fourni par la source)

18 citations Nanomaterials
Accès ouvert 2022 article OpenAlex

Calentamiento de nanopartículas de oro inducido por excitación fotónica y multifotónica

Flonth Viena Gutierrez-Cruz, Alejandra Ancira-Cortez, Miguel A. Camacho‐López, Keila Isaac‐Olivé et autres

Se evalúa la temperatura generada por nanopartículas de oro (AuNPs) al ser irradiadas con luz láser para su utilidad en terapia fototérmica plasmónica fotónica o multifotónica. Las AuNPs fueron sintetizadas por el método de Turkevitch y caracterizadas por técnicas espectroscópicas. La irradiación …

mx (code pays fourni par la source)

0 citations CIENCIA ergo sum
Accès ouvert 2022 article OpenAlex

Controlled-Release Nanosystems with a Dual Function of Targeted Therapy and Radiotherapy in Colorectal Cancer

Pedro Cruz-Nova, Alejandra Ancira-Cortez, Guillermina Ferro‐Flores, Blanca Ocampo‐García et autres

Nanoparticles are excellent platforms for several biomedical applications, including cancer treatment. They can incorporate different molecules to produce combinations of chemotherapeutic agents, radionuclides, and targeting molecules to improve the therapeutic strategies against cancer. These specific nanosystems are designed to have minimal side …

mx (code pays fourni par la source)

22 citations Pharmaceutics
Accès ouvert 2022 article OpenAlex

Targeted Endoradiotherapy with Lu2O3-iPSMA/-iFAP Nanoparticles Activated by Neutron Irradiation: Preclinical Evaluation and First Patient Image

Myrna Luna‐Gutiérrez, Blanca Ocampo‐García, Nallely Jiménez‐Mancilla, Alejandra Ancira-Cortez et autres

Prostate-specific membrane antigen (PSMA) is expressed in a variety of cancer cells, while the fibroblast activation protein (FAP) is expressed in the microenvironment of tumors. Previously, we reported the ability of iPSMA and iFAP ligands to specifically target PSMA and FAP proteins, …

mx (code pays fourni par la source)

17 citations Pharmaceutics

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