Mian Faisal Nazir

Red but not the same: Biochemical, metabolomic and flavoromic analyses reveal signature variations in red-fleshed kiwifruit cultivars

Edgar Manuel Bovio-Zenteno, Mian Faisal Nazir, Tianjiao Jia, Chen Feng et autres

This study employed UPLC-MS/MS and GC-MS metabolomics to analyze quality traits in three red-fleshed kiwifruit cultivars: 'RubyRed', 'Donghong', and 'Hongyang'. 'RubyRed' showed enhanced biosynthesis of flavonoids, particularly anthocyanins, and a volatile profile rich in esters, aldehydes, and ketones contributing to fruity and …

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Stage-specific harvest of Akebia trifoliata flowers: An integrated multi-omics strategy for optimizing natural colorants, antioxidants and bioactive ingredients

Tianjiao Jia, Mian Faisal Nazir, Edgar Manuel Bovio-Zenteno, Chen Feng et autres

The underutilized flowers of Akebia trifoliata represent a promising source of high-value plant-based ingredients. To unlock their potential, we applied an integrated multi-omics approach combining dynamic metabolomics, bioactivity assays, and network pharmacology to analyze metabolic profiles across three developmental stages: bud (S1), …

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Chromosome-Scale Landrace and Elite Genomes of Upland Cotton: Fourteen Lineage-Private Inversions and their Germplasm Distribution, Chromatin Context and Expression Divergence

Mian Faisal Nazir, Hongge Li, Jingjing Wang, Xiuxiu Wang et autres

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Physiological, biochemical and molecular regulatory mechanisms of kiwifruit responses to heat stress: A review and future perspectives

Edgar Manuel Bovio-Zenteno, Tianjiao Jia, Mian Faisal Nazir, Longyu Dai et autres

• Highlights the effects of heat stress on different stages of kiwifruit plant development • Offers an overview of key elements mechanisms induced by heat stress on kiwifruit • Summarizes the available strategies to handle global warming effects on kiwifruit • Presents …

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Integrated transcriptomic and metabolomic analyses delineate the biosynthetic pathways of functional components in maturing Akebia trifoliata fruit

Mian Faisal Nazir, Tianjiao Jia, Feng Chen, Edgar Manuel Bovio-Zenteno et autres

This study integrates transcriptomic and metabolomic analyses across five developmental stages of Akebia trifoliata , a climacteric fruit, to map the molecular mechanisms of fruit maturation. We identified key transcription factors, including NAC, MYB, and AP2/ERF families, and genes orchestrating a stage-specific …

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Widely Targeted Metabolomics Analysis Reveals Developmental Shifts in Antioxidants and Functional Peptides in Akebia trifoliata

Tianjiao Jia, Mian Faisal Nazir, Edgar Manuel Bovio-Zenteno, Longyu Dai et autres

Akebia trifoliata is an emerging fruit crop in China, valued for its medicinal and nutritional properties. To elucidate the developmental dynamics of its bioactive compounds, we performed widely targeted metabolomics using Ultra Performance Liquid Chromatography–Tandem Mass Spectrometry (UPLC-MS/MS) across four fruit developmental …

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Chromosome-level genome assembly of the autotetraploid yellow pitaya provides novel insights into evolution of trait patterning in pitaya species with different ploidy

Qamar U. Zaman, Ali Raza, Hui Liu, Mian Faisal Nazir et autres

BACKGROUND: Yellow pitaya (Selenicereus megalanthus, 2n = 4x = 44) breeding remains severely hindered due to the lack of a reference genome. RESULTS: Here, we present a high-quality chromosome-level genome assembly of yellow pitaya using PacBio HiFi sequencing and Hi-C scaffolding technologies. …

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Metabolomic profiling of Akebia species: Comparative analysis of bioactive compounds in the pulp of A. trifoliata, A. trifoliata ssp. australis, and A. quinata

Mian Faisal Nazir, Tianjiao Jia, Jie Xu, Longyu Dai et autres

(AKQ) are popular for their sweet, aromatic fruits and pharmacological applications. Despite their commercial and medicinal importance, the metabolomic profiles of Akebia pulp remain largely unexplored. This study employs UPLC-MS/MS and GC-MS techniques to comprehensively analyze the chemical composition of the pulp …

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Akebia quinata flower is an excellent potential herbal tea: Chemical quality, bioactivity analysis and metabolite profiles of Akebia quinata flower with different drying methods

Tianjiao Jia, Mian Faisal Nazir, Tao Zhang, Qi Zhu et autres

• Of the three drying methods, microwave drying had the highest content of phenolics, flavonoids and anthocyanins, the strongest antioxidant capacity and improved flavour. • Hot air drying and natural drying retained stronger α-glucoside inhibitory activity and NO inhibitory activity than microwave …

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Deciphering the Genetic and Biochemical Drivers of Fruit Cracking in Akebia trifoliata

Mian Faisal Nazir, Tianjiao Jia, Yi Zhang, Longyu Dai et autres

This study investigates the molecular mechanisms underlying fruit cracking in Akebia trifoliata, a phenomenon that significantly impacts fruit quality and marketability. Through comprehensive physiological, biochemical, and transcriptomic analyses, we identified key changes in cell wall components and enzymatic activities during fruit ripening. …

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The genetic basis of leaf hair development in upland cotton ( Gossypium hirsutum )

Xiaoyang Wang, Panhong Dai, Hongge Li, Jingjing Wang et autres

Trichomes, which originate from the epidermal cell of aerial organs, provide plants with defense and secretion functions. Although numerous genes have been implicated in trichome development, the molecular mechanisms underlying trichome cell formation in plants remain incompletely understood. Here, we using genome-wide …

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Kiwifruit in the Omics Age: Advances in Genomics, Breeding, and Beyond

Mian Faisal Nazir, Jinpeng Lou, Yu Wang, Shuaiyu Zou et autres

The kiwifruit, Actinidia genus, has emerged as a nutritionally rich and economically significant crop with a history rooted in China. This review paper examines the global journey of the kiwifruit, its genetic diversity, and the role of advanced breeding techniques in its …

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