Kim Jemmett

A survey of the workload generated by older surgical patients referred to on-call medical registrars—SNAP-3

Claire J Swarbrick, D Moloney, Tamsin Gregory, Mark MacGregor et autres

Background: Older surgical patients who develop medical problems are commonly referred to medical teams, which can be proactive physician-led teams or through reactive referral to the on-call medical registrar. Methods: A cross-sectional survey of on-call medical registrars who received referrals from surgical …

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Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery

Mark Edwards, Gordon Forbes, Neil Walker, Dion Morton et autres

INTRODUCTION: Postoperative morbidity and mortality in patients undergoing major emergency gastrointestinal surgery are a major burden on healthcare systems. Optimal management of perioperative intravenous fluids may reduce mortality rates and improve outcomes from surgery. Previous small trials of cardiac-output guided haemodynamic therapy …

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Prospective observational cohort study on grading the severity of postoperative complications in global surgery research

Tom Abbott, Kathryn Greaves, A Patel, Tahania Ahmad et autres

BACKGROUND: The Clavien-Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. However, it is unclear whether the Clavien-Dindo system can be used internationally in studies across …

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The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis

Tom Abbott, T. Ahmad, M.K. Phull, A.J. Fowler et autres

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Hyperoxia and surgical site infections

Kim Jemmett

I am concerned about the World Health Organization's (WHO) recent recommendation for preventing surgical site infection (SSI), that 80% oxygen should be administered both intra-operatively and in the immediate postoperative period for 2–6 h 1. The authors of the guideline performed a …

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Preoperative screening for sickle cell disease in children: a pragmatic solution in a UK district hospital

Kim Jemmett, Andrew E. Williams

Sickle cell disease and other hemoglobin disorders are becoming increasingly prevalent across the whole of Europe and hence within our anesthetic practice. Despite this, there still appears to be a largely varied consensus on when preoperative sickle cell testing is necessary in …

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Management of a parturient with a retrosternal goitre and tracheal compression

L. AlShammari, Kim Jemmett, M. Wikner, Nusrat Usman

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A Cyanobacterial Lipopolysaccharide Antagonist Inhibits Cytokine Production Induced byNeisseria meningitidisin a Human Whole-Blood Model of Septicemia

Kim Jemmett, Annalisa Macagno, Monica Molteni, John E. Heckels et autres

Septicemia caused by Neisseria meningitidis is characterized by increasing levels of meningococcal lipopolysaccharide (Nm-LPS) and cytokine production in the blood. We have used an in vitro human whole-blood model of meningococcal septicemia to investigate the potential of CyP, a selective Toll-like receptor …

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