Lidia Irene Staszewsky

Prescription of SGLT-2 inhibitors alone or in combination with RAS-inhibitors in patients with diabetes mellitus and comorbid cardiovascular disease, chronic kidney disease or cardiorenal disease: a real-world evidence study from the REPOSI registry

Paolo Lido, Sara Ratti, Chiara Ronchetti, Marco Infante et autres

it, ch, us (code pays fourni par la source)

Beta-blockers after invasively managed STEMI vs NSTEMI without reduced ejection fraction: a prespecified analysis from the REBOOT trial

Sergio Raposeiras‐Roubín, Manuel Anguita, Roberto Latini, Alberto Domínguez-Rodríguez et autres

es, it (code pays fourni par la source)

Effect of beta blockers in acute and chronic coronary syndromes without reduced ejection fraction: a landmark analysis from the REBOOT trial

Xavier Rosselló, José A. Barrabés, Massimo Piepoli, Alberto Domínguez-Rodríguez et autres

AIMS: Current guidelines recommend beta-blocker therapy after myocardial infarction (MI) regardless of left ventricular ejection fraction (LVEF). However, recent trials question their benefit in patients with preserved LVEF. No study has yet compared beta-blocker effects during the acute coronary syndrome (ACS) phase …

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CardioPulmonary resuscitation with Argon (CPAr): A protocol for a randomised controlled multicentre clinical trial

Giuseppe Ristagno, Lidia Irene Staszewsky, Giulia Merigo, Aurora Magliocca et autres

Aims: in unconscious adults resuscitated from out-of-hospital cardiac arrest (OHCA). Methods: desaturation requiring discontinuation of Ar, and haemodynamic adverse events. Patients are followed up to 6 months, with outcome assessment at ICU/hospital discharge, 1- and 6-months post-CA. A centralized plasma and serum …

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Beta-Blockers after Myocardial Infarction without Reduced Ejection Fraction

Borja Ibáñez, Roberto Latini, Xavier Rosselló, Alberto Domínguez‐Rodríguez et autres

BACKGROUND: Current guideline recommendations for the use of beta-blockers after myocardial infarction without reduced ejection fraction are based on trials conducted before routine reperfusion, invasive care, complete revascularization, and contemporary pharmacologic therapies became standard practice. METHODS: We conducted an open-label, randomized trial …

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When Real-World Outcomes Do Not Meet the Results of Clinical Trials: Transfemoral Transcatheter vs. Surgical Aortic Valve Replacement in an Intermediate-Age Population (The Outstanding Italy Study)

Marco Ranucci, Lidia Irene Staszewsky, Massimo Cartabia, Mauro Tettamanti et autres

Objective: Aortic valve stenosis is the most common valvular heart disease in the elderly, and its treatment may be either surgical (SAVR) or transcatheter (TAVI). Although age is one of the main determinants of the therapeutic choice, current guidelines leave a “discrepancy …

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On the Price of Valoctogene Roxaparvovec in Germany and Italy

Lidia Irene Staszewsky, Alessandro Nobili, Livio Garattini, Pier Mannuccio Mannucci

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445 Effect of indoleamine 2,3-dioxygenase-1 deficiency on long term left ventricle remodeling in a murine model of myocardial infarction

Marianna Cerrato, Daria De Giorgio, Francesca Motta, Carlo Perego et autres

427 Kinetic of inhalatory Argon after cardiac arrest and resuscitation

Daria De Giorgio, Francesca Fumagalli, Aurora Magliocca, Giulia Merigo et autres

Post-cardiac arrest temporal evolution of left ventricular function in a rat model: speckle-tracking echocardiography and cardiac circulating biomarkers

Daria De Giorgio, Davide Olivari, Francesca Fumagalli, Deborah Novelli et autres

Abstract Aims There is little information from experimental studies regarding the evolution of post-resuscitation cardiac arrest [post-return of spontaneous circulation (post-ROSC)] myocardial dysfunction during mid-term follow-up. For this purpose, we assessed left ventricular (LV) function and circulating cardiac biomarkers at different time …

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309 Argon attenuates myocardial injury by modulation of mitochondrial quality control processes in a rat model of cardiac arrest

Marianna Cerrato, Francesca Fumagalli, Francesca Motta, Daria De Giorgio et autres

Characterization of the Cardiac Structure and Function of Conscious D2.B10-Dmdmdx/J (D2-mdx) mice from 16–17 to 24–25 Weeks of Age

Daria De Giorgio, Deborah Novelli, Francesca Motta, Marianna Cerrato et autres

Duchenne muscular dystrophy (DMD) is the most common form of muscle degenerative hereditary disease. Muscular replacement by fibrosis and calcification are the principal causes of progressive and severe musculoskeletal, respiratory, and cardiac dysfunction. To date, the D2.B10-Dmdmdx/J (D2-mdx) model is proposed as …

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