Sascha Rutz

Optimization Leading to a Potent and Selective Cbl-b Inactive-State Inhibitor That Demonstrated In Vivo Efficacy

Jun Liang, Michael J. Lambrecht, Malcolm Huestis, Bingyan Zhu et autres

ca, cn (code pays fourni par la source)

Optimization and In Vivo Characterization of a Series of Cbl-b Inactive-State Inhibitors

Michael J. Lambrecht, Jun Liang, Peter M.U. Ung, Malcolm P. Huestis et autres

ca, cn (code pays fourni par la source)

Loss of the autoimmune risk gene TREX1 reveals a convergence of mechanisms promoting immune tolerance loss and antitumor immunity

Junghyun Lim, Katherine Williams, Stephanie Mittman, Patricia Pacheco Sanchez et autres

Pseudokinase STK40 limits T cell exhaustion through COP1-dependent degradation of AP1-family transcription factors

Svetlana Altshuler-Keylin, Nicole Caduff, Isabel E. Ishizuka, Rohit Reja et autres

us, fr, gb, es (code pays fourni par la source)

QSP model trained on preclinical data informs clinical dose selection for a T-cell engaging bispecific antibody for solid tumor indications

Phillip Spinosa, Hao Cai, Iraj Hosseini, Teemu T. Junttila et autres

282 Improving solid tumor CAR-T therapies by modulating T cell transcriptional states using combinatorial in vitro CRISPR screening followed by in vivo validation

Lina M León, Angela C. Boroughs, Ashley Cass, Andrew Cardozo et autres

us (code pays fourni par la source)

385 Identification of TCRs targeting shared tumor antigens

Ilseyar Akhmetzyanova, Josefa Chuh, Kathy Kozak, Sascha Rutz et autres

334 Computational mapping of CAR-T cell exhaustion through single-cell perturbation screens

Li Wang, David DeTomaso, Ashley Cass, Julie Chow et autres

us (code pays fourni par la source)

A real-time antibody-dependent cellular phagocytosis assay by live cell imaging

Yongchang Shi, Yonglian Sun, Akiko Seki, Sascha Rutz et autres

gb (code pays fourni par la source)

Optimization of a Novel DEL Hit That Binds in the Cbl-b SH2 Domain and Blocks Substrate Binding

Jun Liang, Michael J. Lambrecht, Teresita L. Arenzana, Samuel Aubert‐Nicol et autres

ca, ch, cn (code pays fourni par la source)

Author Correction: c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host–microbiota homeostasis

Christian Neumann, Jonas Blume, Urmi Roy, Peggy P. Teh et autres

de, au, nl, ru, fr (code pays fourni par la source)

An image-based real time method to measure antibody-dependent cellular phagocytosis

Yongchang Shi, Jianyong Wang, Yonglian Sun, James T. Koerber et autres