Accès ouvert
2026
article
OpenAlex
Casey Kraft, John C. Bischof, Erik B. Finger
Extending donor organ preservation times would substantially improve patient outcomes by widening safety margins and enabling better donor-to-patient matching. While clinical 4°C static storage typically preserves donor kidneys for 18–24 h, donor hearts are limited to ∼4 h. This clinical disparity is …
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2026
article
OpenAlex
Homayra Mumu, Yujie Luo, Joseph Kangas, John C. Bischof et autres
Precise spatial control of light-induced heating is critical across photothermal applications ranging from laser therapies to materials processing yet remains difficult in the presence of complex refractive interfaces. For example, laser warming of cryopreserved specimens requires uniform, rapid heating, but refractive distortions …
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Accès ouvert
2026
preprint
OpenAlex
Joseph R. Kangas, Abhilash Ojha, Minhan Jiang, Mohammad Shameem et autres
Cell therapies hold transformative potential for treating cancer, neurologic disorders, organ failure, diabetes, and other conditions, but their widespread clinical deployment is constrained by the lack of scalable cryopreservation methods that maintain high post-thaw viability. Current standard practice using slow freezing can …
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Accès ouvert
2026
preprint
OpenAlex
Homayra Mumu, Yujie Luo, Joseph R. Kangas, John C. Bischof et autres
Precise spatial control of light-induced heating is critical across photothermal applications ranging from laser therapies to materials processing, yet remains difficult in the presence of complex refractive interfaces. For example, laser warming of cryopreserved specimens requires uniform, rapid heating, but refractive distortions …
us
(code pays fourni par la source)
Accès ouvert
2026
preprint
OpenAlex
Homayra Mumu, Yujie Luo, Joseph R. Kangas, John C. Bischof et autres
Precise spatial control of light-induced heating is critical across photothermal applications ranging from laser therapies to materials processing, yet remains difficult in the presence of complex refractive interfaces. For example, laser warming of cryopreserved specimens requires uniform, rapid heating, but refractive distortions …
us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Mary Hagedorn, Lynne R. Parenti, Robert A. Craddock, Pierre Comizzoli et autres
Earth’s resources are essential to support an expanding presence beyond the planet. Yet global conflicts, environmental change, and natural disasters threaten ecosystems and biodiversity, putting the integrity of Earth’s ecosystems and its resources at risk. These converging challenges underscore the urgency to …
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Accès ouvert
2026
article
OpenAlex
Michael G. Megaly, Diane K. Tobolt, A. W. Chen, Bat‐Erdene Namsrai et autres
Abstract Hepatic spheroids are widely used in bioartificial liver (BAL) systems, hepatotoxicology, and pharmacology due to improved functional stability compared with monolayer cultures. However, many existing methods rely on specialized equipment or static platforms that limit scalability and dynamic culture applications. Primary …
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Accès ouvert
2026
article
OpenAlex
Lakshya Gangwar, Dorothy M. Haggard, Michael L. Etheridge, Mark B. Shiflett et autres
Cryopreservation relies on refrigerants for achieving and sustaining ultra-low (>−150 °C) or cryogenic temperatures (<−150 °C) for cooling, transport and storage of biological materials. Liquid nitrogen (LN 2 ) remains the standard refrigerant in cryobiology due to its low cryogenic boiling point, …
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Accès ouvert
2026
article
OpenAlex
Christopher M. Fang-Yen, Daryl M. Gohl, Jonathan D. Hibshman, Estefania Paredes et autres
The ability to preserve small invertebrate organisms indefinitely at ultracold temperatures has been an important tool for biological and biomedical research. This report provides a summary of an NIH-sponsored workshop on Cryopreservation and Other Preservation Approaches for Invertebrate Models. This workshop addressed …
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Accès ouvert
2026
other
OpenAlex
Onyinyechukwu Justina Oziri, Cameron Scheithauer, Henry L. Wong, Michael L. Etheridge et autres
Abstract The ability to cryopreserve and rewarm whole organs without damage has the potential to transform transplantation by enabling long-term banking and global organ sharing. Successful transplantation of rat kidneys cryopreserved and rewarmed using nanowarming, a technique in which silica coated iron …
us
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Accès ouvert
2026
other
OpenAlex
Onyinyechukwu Justina Oziri, Cameron Scheithauer, Henry L. Wong, Michael L. Etheridge et autres
Abstract The ability to cryopreserve and rewarm whole organs without damage has the potential to transform transplantation by enabling long-term banking and global organ sharing. Successful transplantation of rat kidneys cryopreserved and rewarmed using nanowarming, a technique in which silica coated iron …
us
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Accès ouvert
2026
article
OpenAlex
Onyinyechukwu Justina Oziri, Cameron Scheithauer, Henry L. Wong, Michael L. Etheridge et autres
Supplementary material 1.
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