Muhammad Zohaib Rafay

Proximate and Phytochemical Investigations Probing Antioxidant and Antiepileptic Potential of Terminalia bellirica Roxb. Leaf Extracts: An In Silico Validation Study

Aneeqa Saleem, Muhammad Islam, Abrar Ahmed, Muhammad Zohaib Rafay et autres

ABSTRACT Terminalia bellirica Roxb. is a well‐known medicinal plant with diverse therapeutic uses. This study investigated the phytochemical profile of T. bellirica leaf extracts, their antiepileptic activity in an acute pentylenetetrazole (PTZ)‐induced seizure model, and the in silico validation of GC–MS–identified metabolites. …

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Antidiabetic Bioactive Compounds from Juglans regia L. Fruit Endocarp: Isolation, Characterization, and In Silico Molecular Dynamics Simulations

Muhammad Zohaib Rafay, Md. Nahidul Islam, Abrar Ahmed, Hamid Saeed et autres

Abstract This study explores the antidiabetic potential of bioactive compounds isolated from Juglans regia Linn. fruit endocarp fractions. The ethanolic extract was screened for α ‐amylase inhibition, revealing the chloroform fraction as the most potent (18.45 ± 0.76%), followed by the n …

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Sulfamethoxazole-derived Schiff bases: Synthesis, characterization, biological activities, molecular docking, DFT, and ADME studies

Muhammad Wajid, Muhammad Uzair, Gulzar Muhammad, Farhan Siddique et autres

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EVALUATION OF MEDICATION KNOWLEDGE, ATTITUDES AND SELF MEDICATION PRACTICES AMONG PHARMACY STUDENTS

Fahad Asim, Hafiz Muhammad Ramzan, Sarwat Ali Raja, Kanwal Mazhar et autres

Self-medication has become prevalent in the modern era and can lead to serious adverse drug reactions and drug interactions. Hence, this study was carried out to evaluate and assess the knowledge, attitudes and practices of medication use among pharmacy students of the …

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Insight to phytochemical investigation and anti-hyperlipidemic effects of Eucalyptus camaldulensis leaf extract using in vitro , in vivo and in silico approach

Hafiza Arbab Hussain, Muhammad Islam, Hamid Saeed, Abrar Ahmad et autres

Hyperlipidemia is a key risk factor mainly for hypertension and cardiac abnormalities. Previously eucalyptus plant (river red gum) had been used for its medicinal value for the treatment of many ailments. This study focused on phytochemical examination, investigation of an in vitro …

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Phytochemical Screening and in vitro Anti-urolithiatic Activity of Fruit-seed Extracts of Melia azedarach

Abida Latif, Faiza Azhar, Muhammad Zohaib Rafay, Muhammad Ahsan Iqbal et autres

Melia azedarach L. has been utilized in traditional systems of medicine for the treatment of various diseases including urolithiasis. The study aimed to perform phytochemical studies and anti-urolithiatic potential of fruit-seed extracts of Melia azedarach. Sequential extraction was performed using chloroform, methanol …

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Phytochemical profiling and anti-inflammatory potential of

in vivo, in silico study Itique Munawar, Muhammad Islam, Abrar Ahmed et autres

Inflammation is immune response of body against foreign toxic substances.Chronic inflammation is associated with diabetes, heart diseases, arthritis and cancer.The present study aims to investigate anti-inflammatory potential of plant Ficus natalensis subspecies leprieurii.Various extracts of leaves of F. natalensis were investigated for …

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Preliminary Studies and In-vitro Antioxidant Activity of Fruit-Seed Extracts of Melia azedarach Linn

Faiza Azhar, Abida Latif, Muhammad Zohaib Rafay, Ahsan Iqbal et autres

Melia azedarach is a medicinal plant utilized for the treatment of various disorders in Asian countries. The antioxidant potential of fruit-seeds from this plant was investigated using n-hexane, chloroform, methanol and aqueous extracts. Preliminary studies were performed on powder as well as …