Joesph R Wiencek

Sample volume management: the role of the clinical laboratory in minimizing diagnostic blood loss

Ana-Maria Šimundić, Snežana Jovičić, Michael Cornes, Antoine Guillon et autres

Hospital-acquired anemia is highly prevalent and largely preventable complication of hospitalization, affecting up to 40-74 % of patients and up to 90 % of intensive care units patients. Excessive diagnostic blood loss from routine phlebotomy represents a significant and modifiable contributor, with …

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Sustainability through Evidence-Based Equations: A Pilot Study Modeling the Friedewald and NIH–Sampson Equations

Stephanie A Hart, Joesph R Wiencek

TO THE EDITOR: Low-density lipoprotein cholesterol (LDL-C) is an important metric for risk stratifying cardiovascular disease and therapeutic monitoring (1, 2). The gold standard for measuring LDL-C is beta-quantification; however, this technology is labor- and resource-intensive (1). As a result, most laboratories …

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Commentary on Unraveling a Clinical Coagulation Paradox: The Laboratory’s Investigative Role

Joesph R Wiencek

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Ethics through the Years: The Evolution of Ethical Guidelines for ADLM

Melissa M. Budelier, Nilda E. Fink, Joesph R Wiencek

The Association for Diagnostics & Laboratory Medicine (ADLM) has published ethical guidelines for laboratory medicine (1–3). These guidelines have undergone several revisions since they were first published in 1953, with the most recent revision published in 2020. We reviewed 5 available (2003 …

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Changes in Access to Comprehensive Clinical Microbiology Laboratory Testing in Tennessee From 2019–2024

Kaleb Wolfe, Stephanie A Hart, Stacy Curry‐Johnson, Ayesha Khan et autres

Background: Timely clinical microbiology laboratory testing is crucial for effective infectious disease management, impacting antibiotic selection, patient outcomes, and health care costs. This study aimed to evaluate changes in geographic access to comprehensive (Tier 1) clinical microbiology laboratories in Tennessee between 2019 …

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The Impact of Raising the Hypoglycemia Critical Value Alert Threshold at an Academic Medical Center

Stephanie A Hart, Scott D. Nelson, Ryan F. Schell, Joesph R Wiencek

To the Editor: In 2019, the American Diabetes Association (ADA) released new guidance that classified level 2 hypoglycemia as glucose values <54 mg/dL [3.0 mmol/L] (1). This threshold was adopted based on a 2017 consensus report that defined 54 mg/dL [3.0 mmol/L] …

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376 Validation of the Lidocaine Syva EMIT™ Assay on the Roche cobas 503 System

Joesph R Wiencek

Abstract Introduction/Objective Lidocaine is a class IB antiarrhythmic with a narrow therapeutic index. The lidocaine Syva EMIT™ is a third-party FDA-approved assay adaptable to several automated chemistry platforms. Although assay parameters exist for the Roche cobas c502, they are unavailable for Roche …

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459 Potential Savings of Two Practical Interventions on Vitamin D Ordering Practices at a Large Academic Medical Center

Stephanie A Hart, Jeremy Brown, Joesph R Wiencek

Abstract Introduction/Objective Endocrine Society Clinical Practice Guideline for Vitamin D recommends against routine 25-hydroxyvitamin D (TVD) testing in adults. This study aims to assess unnecessary TVD testing in the adult primary care setting to identify practical solutions to reduce waste. Methods/Case Report …

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Potential savings of two practical interventions on vitamin D ordering practices at a large academic medical center

Stephanie A Hart, Jeremy Brown, Joesph R Wiencek

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Estimated waste generation from 1 million basic metabolic panels: a multisite U.S. study

Seema Khattri Bhandari, Kwaku Twum, Erving T. Laryea, Yaqing Du et autres

Abstract Objectives Clinical laboratory operations consume large amounts of electricity and water and generate considerable quantities of solid waste. In this study, we quantified and compared the estimated solid waste produced from performing one million basic metabolic panels (BMPs) across five major …

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A Practical Guide to Advancing Your Career: Laboratory Medicine Maxims

Maximo J Marin, Xander M.R. van Wijk, Joesph R Wiencek

Joseph Simone, an academic physician, authored Simone’s Maxims to guide professionals through the many complexities of academic medicine (1). With workplace burnout and negative culture widespread in clinical laboratories, training programs, and pathology/laboratory medicine departments (2, 3), we revisited and adapted Simone’s …

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Price Variability of Eight Common Laboratory Tests across All Licensed Tennessee Hospitals

Stephanie A Hart, Ayesha Khan, Garrett S. Booth, Joesph R Wiencek

BACKGROUND: In 2021, the United States implemented a federal price transparency mandate to help combat price variability across the country. Initial studies conducted within several months of the mandate showed persistent price variability. METHODS: To assess continued price variability for laboratory tests …

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