1237-P: Generation of Targeted Nanoparticles for ß-Cell-Selective Delivery of Antioxidant Drugs
ALISSA NOVAK, Tanmaye Nallan Chakravarthula, Justin J. Crowder, Nathan J. Alves et autres
β-cells are highly metabolic and vulnerable to a variety of exogenous stressors, many of which elicit the generation of reactive oxygen species (ROS). Endogenous adaptive responses can restore homeostasis after excessive ROS elevation. If the endogenous adaptive response fails, ROS accumulation can …
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