Wai Fu Ng

POS0657 UNDERSTANDING DISEASE PROGRESSION IN PATIENTS WITH SJÖGREN'S DISEASE: INSIGHTS FROM THE UNITED KINGDOM PRIMARY SJÖGREN'S SYNDROME REGISTRY

Wai Fu Ng, C. Matilda Collins, A. Christodoulou, Kirti Mirchandani et autres

Background: Sjögren's disease (SjD) is a chronic, progressive, autoimmune disease that affects the entire body, with a global prevalence of 0.01% to 3%, predominantly among women. Symptoms typically appear in the middle age group (45-55 years). Clinical manifestation of symptoms varies among …

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ADULT LANGERHANS CELL HISTIOCYTOSIS WITH MULTISYSTEM INVOLVEMENT

Wai Fu Ng, Norasyikin Abdul Wahab

INTRODUCTION/BACKGROUNDLangerhans cell histiocytosis (LCH) is a rare, heterogenous disease with a wide range of manifestations, from unifocal lesions to multisystem involvement. Commonly affected sites include the bone, lungs, pituitary gland, liver, bone marrow, and skin. We report a case of adult-onset LCH …

INDIVIDUALIZED MANAGEMENT STRATEGIES FOR VERY SEVERE HYPERTRIGLYCERIDEMIA

Jaarvis Verasingam, Ijaz Hallaj Rahmatullah, Anilah Abdul Rahim, Wai Fu Ng

INTRODUCTION/BACKGROUNDVery severe hypertriglyceridemia (HTG) is defined by the Endocrine Society as a serum triglyceride concentration ≥22.6 mmol/L. Management typically involves dietary modification, pharmacotherapy such as fibrates combined with statins, insulin therapy, and plasmapheresis in select cases. We report two cases of non-familial …

SUCCESSFUL WEIGHT LOSS POST-BARIATRIC SURGERY

Chooi Fun Tean, Siew Wai Shuit, Wai Fu Ng, Ijaz Hallaj Rahmatullah et autres

INTRODUCTIONThis study aims to determine the percentage of patients who achieved successful weight loss at 12 months post-bariatric surgery. Successful weight loss is defined as achieving at least 50% excess weight loss (EWL) within one to two years. METHODOLOGYWe conducted a retrospective …

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Prevalence of Anaemia and Related Micronutrient Deficiencies After Bariatric Surgery

Wai Fu Ng, Ijaz Hallaj Rahmatullah, Norasyikin binti A. Wahab, Chee Xian Tan et autres

Purpose: Anaemia and micronutrient deficiencies are common complications following bariatric surgery. This study aimed to determine the prevalence of anaemia after Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG), and to identify anaemia associated risk factors. Materials and Methods: A cross-sectional study …

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Paediatric hepatic angiosarcoma with consumptive hypothyroidism—an important diagnostic pitfall to avoid during evaluation of hepatic vascular tumours

Dickson Fenn, Kin Fen Kevin Fung, Anthony Pak‐Yin Liu, Wai Fu Ng et autres

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THE USE OF THERAPEUTIC PLASMA EXCHANGE IN A PATIENT WITH RECURRENT SEVERE HYPERTRIGLYCERIDEMIA-INDUCED ACUTE PANCREATITIS

Wai Fu Ng, Wan Jane Liew

INTRODUCTION/BACKGROUNDSevere hypertriglyceridemia (HTG)-induced acute pancreatitis is defined by clinical, laboratory and radiographic evidence of acute pancreatitis with triglyceride (TG) levels of >11.2 mmol/L in the absence of other causative factors. We report a case of therapeutic plasma exchange (TPE) used in recurrent …

ENDOSCOPIC ULTRASOUND-GUIDED RADIOFREQUENCY ABLATION USED IN THE TREATMENT OF INSULINOMA

Wai Fu Ng, Xin Ning Lee, Anilah Abdul Rahim, Ijaz Hallaj Rahmatullah

INTRODUCTION/BACKGROUNDSurgical excision used to be the mainstay of curative treatment for insulinoma. In recent years, endoscopic ultrasound-guided radiofrequency ablation (EUS-guided RFA) has been used as a curative technique for insulinoma. Here, we report 2 cases of insulinoma with solitary lesions which showed …

Epidemiology and outcomes of pediatric transplant‐associated thrombotic microangiopathy in Hong Kong

Wilson Yau Ki Chan, Eugene Yu-hin Chan, Amanda Kan, Wai Fu Ng et autres

BACKGROUND: Transplant-associated thrombotic microangiopathy (TA-TMA) is an under-recognized yet potentially devastating complication of hematopoietic stem cell transplantation (HSCT) which had increased awareness in recent years. This report summarizes the demographics and outcomes of pediatric TA-TMA in Hong Kong. METHODS: All patients aged …

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A CASE OF GRAVES’ DISEASE WITH SEVERE HYPERCALCAEMIA

Wai Fu Ng

INTRODUCTION Mild to moderate hypercalcemia is seen in up to 20 percent of thyrotoxic patients. However, thyroid hormone-mediated severe hypercalcemia is rare. We report a case of Graves disease-induced symptomatic severe hypercalcemia. CASE A 25-year-old male presented with a three-week duration of …

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A Fetus with Congenital Microcephaly, Microphthalmia and Cataract Was Detected with Biallelic Variants in the OCLN Gene: A Case Report

Vivian Kwun Sin Ng, Tze Kin Lau, Anita Sik Yau Kan, Brian Hon‐Yin Chung et autres

Microcephaly and microphthalmia are both rare congenital abnormalities, while concurrently, these two are even rarer. The underlying etiology would be complex interplaying between heterogeneous genetic background and the environmental pathogens, particularly during critical periods of early tissue development. Here, we reported a …

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Enterovirus 71 encephalomyelitis and Japanese encephalitis can be distinguished by topographic distribution of inflammation and specific intraneuronal detection of viral antigen and RNA

Kum Thong Wong, Koi Yee Ng, Kien Chai Ong, Wai Fu Ng et autres

K. T. Wong, K. Y. Ng, K. C. Ong, W. F. Ng, S. K. Shankar, A. Mahadevan, B. Radotra, I. J. Su, G. Lau, A. E. Ling, K. P. Chan, P. Macorelles, S. Vallet, M. J. Cardosa, A. Desai, V. Ravi, N. …

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