Sergey M. Korotkov

Stimulating effect of low concentrations of Eu3+ on spontaneous cardiac contractions

K. V. Sobol, Sergey M. Korotkov, И. В. Шемарова, В. П. Нестеров

The negative cumulative effects of lanthanides on the human body are well known; they are associated mainly with the toxic effects of rare earth metals (REE) on muscle tissue. However, the effects of low concentrations of these metals on muscle are less …

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On the History of Studying of Biological Motility at the Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences

А. И. Бурдыгин, Karolina Ivanov, Sergey M. Korotkov, K. V. Sobol et autres

On the occasion of the 90th birthday of Vladimir Petrovich Nesterov, a group of research scientists and a brigade of colleagues who have worked with him in the past in the laboratory of functional biochemistry of muscles (known as Laboratory № 18) …

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Stimulatory Effect of Low Concentrations of Eu3+ on Spontaneous Cardiac Contractions

K. V. Sobol, Sergey M. Korotkov, I. V. Schemarova, В. П. Нестеров

Negative cumulative effects of lanthanides on the human body are well known; they are mainly related to the toxic effects of rare earth metals (REE) on muscle tissue. However, the effects of low concentrations of these metals on muscle are much less …

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Mitochondrial Oxidative Stress Is the General Reason for Apoptosis Induced by Different-Valence Heavy Metals in Cells and Mitochondria

Sergey M. Korotkov

This review analyzes the causes and consequences of apoptosis resulting from oxidative stress that occurs in mitochondria and cells exposed to the toxic effects of different-valence heavy metals (Ag+, Tl+, Hg2+, Cd2+, Pb2+, Al3+, Ga3+, In3+, As3+, Sb3+, Cr6+, and U6+). The …

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On the possibility of non-invasive study of the peripheral mechanisms of autonomous regulation of the human cardiovascular system

В. П. Нестеров, А. И. Бурдыгин, Karolina Ivanov, Sergey M. Korotkov et autres

The aim of this study was to evaluate the possibility of using the developed method of arterial piezopulsometry for non-invasive study of peculiarities of the functioning of peripheral mechanisms of autonomic regulation of the cardiovascular system in patients of different age and …

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On the Possibility to Noninvasively Study the Peripheral Mechanisms of Autonomic Regulation of the Human Cardiovascular System

В. П. Нестеров, А. И. Бурдыгин, Karolina Ivanov, Sergey M. Korotkov et autres

Abstract The study evaluated the possibility of using the original arterial piezo pulsometry (APP) method to noninvasively assess the functional specifics in peripheral mechanisms of autonomic regulation of the cardiovascular (CC) system in patients varying in age and health status. Variability of …

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A Comparative Study on the Effects of the Lysine Reagent Pyridoxal 5-Phosphate and Some Thiol Reagents in Opening the Tl+-Induced Mitochondrial Permeability Transition Pore

Sergey M. Korotkov

Lysine residues are essential in regulating enzymatic activity and the spatial structure maintenance of mitochondrial proteins and functional complexes. The most important parts of the mitochondrial permeability transition pore are F1F0 ATPase, the adenine nucleotide translocase (ANT), and the inorganic phosphate cotransporter. …

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Erythrocyte Respiratory Activity of the Mitochondrial Complex of the Black Sea Thornback Ray (Raja clavata L.) under the Influence of Certain Activators and Inhibitors In Vitro

Yu. A. Silkin, Mikhail Yu. Silkin, Sergey M. Korotkov, Elizaveta N. Silkina et autres

Global warming implies the risk of a changing oxygen regime in the seas and oceans of our planet. The mitochondrial complex of nuclear erythrocytes of cartilaginous fish, as the energy basis of blood cells, has repeatedly encountered such climatic fluctuations throughout their …

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Effect of Eu3+ on Calcium-Dependent Processes in Vertebrate Myocardium

Sergey M. Korotkov, K. V. Sobol, A. V. Novozhilov, В. П. Нестеров

Abstract The inotropic and chronotropic effects of Eu3+ on spontaneous atrial contraction of the frog Rana ridibunda myocardium at different temperatures were studied, as well as the effects of Ca2+ and Eu3+ on isolated rat heart mitochondria, energized with glutamate and malate …

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The Joint Influence of Tl+ and Thiol-Modifying Agents on Rat Liver Mitochondrial Parameters In Vitro

Sergey M. Korotkov

Recent data have shown that the mitochondrial permeability transition pore (MPTP) is the complex of the Ca2+-modified adenine nucleotide translocase (ANT) and the Ca2+-modified ATP synthase. We found in a previous study that ANT conformational changes may be involved in Tl+-induced MPTP …

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Effect of thallium on mitochondria

Sergey M. Korotkov

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Toxic thallium effects on cells

Sergey M. Korotkov

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