Jinhua Lu

Tissue-Resident Cytotoxic γδT Cells in Anti-tumor Immunity 2258876

Yonghao Liu, Yuan Song, Jinhua Lu, Haiyan Liu

Abstract Introduction Tissue-resident αβT cells are well-documented to play a critical role in controlling solid tumors. In contrast, the characteristics and function of tissue-resident γδT cells remain poorly understood. γδ;T cells are a heterogeneous T cell population characterized by phenotypic diversity and …

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GSDME-Mediated Pyroptosis Suppresses Anti-Tumor Immunity via IL-1α—Dependent Recruitment of Immunosuppressive Myeloid Cells 2309550

Yu Mei, Haiyan Liu, Jinhua Lu, Lionel Chin Yong Chew

Abstract Introduction Pyroptosis is widely recognized as an immunogenic form of cell death that promotes anti-tumor immunity. Gasdermin E (GSDME), cleaved by caspase-3 in tumor cells, has therefore been proposed as a tumor suppressor. Here, we report an unexpected immunosuppressive role of …

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[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin et autres

, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for …

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Association of acupuncture timing and treatment intensity with short-term functional recovery in stroke rehabilitation inpatients: a retrospective cohort and prediction study

Yanling Gao, Jiajun Kang, Ting Rao, Jinhua Lu et autres

Background In inpatient stroke rehabilitation settings where acupuncture is part of routine care, several practical questions arise: when treatment should begin, how intensively it should be delivered, and whether data on treatment patterns can help guide individualized discharge planning. We examined treatment-pattern …

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Global, regional, and national burden for major depressive disorders and dysthymia in adults aged 55 years and older, 1990–2021

Yangsheng Liu, Genyuan Li, Yichen Wu, Mingyang Yuan et autres

Depression is one of the major causes of mental illness worldwide. The purpose of this study is to describe the disease burden caused by depression among the elderly in the Global Burden of Disease Study (GBD) 2021. We used GBD 2021 study …

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Validity and predictability of mid-upper arm circumference for nutrition screening in outpatient preschoolers with cerebral palsy

Hongyu Zhou, Tingting Peng, Mou Wei, Jingbo Zhang et autres

Aim: Evaluating the nutritional status of children with cerebral palsy (CP) is difficult due to spasticity and contractures. Mid-upper arm circumference (MUAC) is a potential screening tool for malnutrition in children with CP, but its effectiveness is unproven. This study aims to …

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Rationale and protocol for a longitudinal cohort study of children with cerebral palsy in China assessing functional developmental trends, genetic aetiology and imaging

Tingting Peng, Jinling Li, Zhaoyao He, Jie Luo et autres

INTRODUCTION: Cerebral palsy (CP), the most common physical disability in children, imposes substantial economic and psychological burdens on families and society. The clinical management of CP remains challenging due to the limited efficacy of current treatments and the heterogeneity of its aetiologies …

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The relationship between functional status and hematological parameters in children with spastic cerebral palsy: a retrospective cross-sectional study

Hong Su, Jie Luo, Mingshan Han, Yuan Zhang et autres

Background: Muscle spasms, joint stiffness, dysphagia, dystrophy, and other problems associated with cerebral palsy (CP) might lead to abnormalities in some hematological parameters, yet the characteristics of common hematological parameters in children with spastic CP and the relationship between abnormality of hematological …

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Technical Transformation Scheme and Practice Applied in Ultra-high Share of Renewable Energy Power System at County-level Scale

Ping Xiong, Yu Sun, Lie Li, Jinhua Lu et autres

The rapid integration of variable renewable energy into county-level power grids has introduced significant operational challenges, particularly transmission congestion and transformer overload caused by bi-directional flow. To overcome the restriction of conventional grid reinforcement solutions focused mainly on infrastructure expansion, the work …

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Maternal inflammation during the second trimester of pregnancy with adverse birth outcomes: a prospective cohort study

Wanqing Xiao, S Q Zhu, Qiuming He, Xishan Li et autres

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Guilu erxian glue alleviates chemotherapy-induced myelosuppression by regulating histone methylation level of p16 gene in hematopoietic stem cells

Menglei Wang, J W Wang, Weizhi Lai, Zhaohuan Lou et autres

Background: Myelosuppression is a common chemotherapy-related toxicity and hematopoietic stem cells (HSCs) senescence is the main mechanism. Guilu Erxian Glue (GEG) is an effective Chinese herbal prescription for the treatment of myelosuppression in clinical, the potential mechanism needs further investigation. Objective: To …

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Microstructure and Mechanical Properties Characteristics of 2319 Aluminum Alloy Fabricated Using Cold Metal Transfer Pulsed Advanced (CMT-PADV) Wire Arc Additive Manufacturing

Wenzhuo Bian, Jun Wang, Qing Li, Jinhua Lu et autres

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