Takuma Yoshida

Scissor‐Type Knife Improves Trainee's Self‐Completion of Endoscopic Submucosal Dissection for Early Gastric Cancer

Hayato Fukui, Osamu Dohi, N. Iwai, Mayuko Seya et autres

BACKGROUND: This retrospective study aimed to verify the efficacy of endoscopic submucosal dissection (ESD) using a scissor-type knife for early gastric cancer (EGC). METHODS: The patients who underwent ESD for EGC between April 2014 and March 2022 were enrolled. The primary endpoint …

jp, us (code pays fourni par la source)

Analytical Evaluation of the 2‐in‐1 Adaptive Design for Binary Endpoints

Gosuke Homma, Takuma Yoshida

To reduce drug development costs and time in therapeutic areas with high unmet medical needs, sponsors are often motivated to accelerate the drug development process, specifically by skipping the Phase 2 trial and starting the Phase 3 trial directly after the Phase …

jp (code pays fourni par la source)

Asymptotic Theory for Extreme Value Generalized Additive Model

Takuma Yoshida

jp (code pays fourni par la source)

Single‐index models for extreme value index regression

Takuma Yoshida

ABSTRACT Since the extreme value index (EVI) controls the tail behavior of the distribution function, the estimation of EVI is a very important topic in extreme value theory. Recent contributions have focused on nonparametric regression approaches with covariates for the estimation of …

jp (code pays fourni par la source)

Exact power and sample size in clinical trials with two co-primary binary endpoints

Gosuke Homma, Takuma Yoshida

Binary endpoints are used widely to evaluate treatment effects during clinical trials. Although clinical trials in many therapeutic areas evaluate a single binary endpoint as the primary endpoint, clinical trials in certain therapeutic areas require two co-primary binary endpoints to evaluate treatment …

jp, gb (code pays fourni par la source)

Toward Future Reanalyses That Meet Evolving Needs in Science, Public Services, Policymaking, and Socioeconomic Activity

Hisashi Nakamura, Shinya Kobayashi, Maureen Anyango Wanzala, Fanny Adloff et autres

Reanalysis goes back to the dawn of modern operational numerical weather prediction (NWP). Relying on using a consistent data assimilation system for an extended period back in time at reduced resolution to manage cost, reanalysis integrates historical observations into physically consistent gapless …

jp, cn, ch, de, gb, us, in, ie, it, au, ph, Cameroun, gr (code pays fourni par la source)

Early initiation of oral intake on length of hospital stay in postoperative patients admitted to the intensive care unit

Akiko Takemoto, Yukari Fukuda, Takashi Iwaanakuchi, Takuma Yoshida et autres

Early oral intake is recommended for postoperative recovery. We determined whether early oral intake affects postoperative hospital stay. Using the diagnosis procedure combination system introduced in Japan in 2003, patients were classified into major diagnostic categories (MDC) to determine whether the postoperative …

jp (code pays fourni par la source)

Mechanical Efficacy Equivalence of W-Arch and Quad-Helix Orthodontic Arch Expansion Appliances: A Finite Element Study

Aiko Kamoi, Yukiko Yokoi, Takuma Yoshida, Atsushi Otsuka et autres

The quad-helix and W-arch are commonly used appliances for expanding the dental arch in orthodontic treatment. However, differences in performance between these two expanders remain unclear, and no guidelines exist for selecting one over the other. The purpose of this study was …

jp (code pays fourni par la source)

Mixed effects models for extreme value index regression

Koki Momoki, Takuma Yoshida

Extreme value theory (EVT) provides an elegant mathematical tool for the statistical analysis of rare events. When data are collected from multiple population subgroups, because some subgroups may have less data available for extreme value analysis, a scientific interest of many researchers …

jp (code pays fourni par la source)

Sure independence screening for covariate-dependent extreme value index estimation

Takuma Yoshida, Yuta Umezu

One of the main topics in extreme value analysis is the estimation of the extreme value index, which characterizes the tail behavior of a distribution. Although covariate dependent extreme value index estimation has been widely studied, covariate screening for high-dimensional covariates has …

Impaired immunoproteasomal function exacerbates renal ischemia-reperfusion injury

Yasushi Ishii, Aya Fukui‐Miyazaki, Sari Iwasaki, Takahiro Tsuji et autres

Oxidative stress caused by reactive oxygen species (ROS) is involved in the pathogenesis of renal ischemia-reperfusion injury (I/R injury), a major cause of acute kidney injury and delayed graft function (DGF). DGF is an early transplant complication that worsens graft prognosis and …

jp (code pays fourni par la source)

Hypothesis testing for varying coefficient models in tail index regression

Koki Momoki, Takuma Yoshida

Abstract This study examines the varying coefficient model in tail index regression. The varying coefficient model is an efficient semiparametric model that avoids the curse of dimensionality when including large covariates in the model. In fact, the varying coefficient model is useful …

jp (code pays fourni par la source)