Jia Li

Twin‐Image Free Multichannel Vectorial Holography With Nonlinear Chiroptical Metasurfaces

Jiafei Chen, Zixian Hu, Bingbing Li, Rong Rong et autres

ABSTRACT Multichannel vectorial holography has essential applications in the fields of optical information processing and optical communications. With the development of metasurface devices, multiple vortex beams and holographic images with vectorial polarization distributions have been demonstrated in both linear and nonlinear optical …

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Mechanism of Saikosaponin D in regulating ferroptosis in patient-derived lung adenocarcinoma organoids via upregulation of ATF3/CHOP/CHAC1 signaling

Jia Li, Qiong Ma, Chunxia Huang, Xiao Zeng et autres

Lung adenocarcinoma (LUAD) is associated with high morbidity and mortality, making the discovery of novel and effective drugs treatment crucial.This study aimed to identify and evaluate antitumor saponin monomers with better effects using patient-derived organoid (PDO) models from patients with LUAD. We …

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Compositional Engineering for Low-Dark-Current Perovskite X-ray Detectors

Mengpei Zhang, Shuai Sun, Wenjie Chen, Muhammad Irfan et autres

Polycrystalline perovskites have attracted extensive interest in the field of X-ray detection/imaging due to their excellent compatibility with scalable processing. However, despite recent advances, polycrystalline perovskite X-ray direct detectors are plagued by the relatively high dark currents in imaging applications. Herein, we …

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ALDH3A1-dependent Nrf2/HO-1/GPX4 pathway supports AHR as a promising therapeutic target for ferroptosis and promotes imperatorin-mediated lung protection

Xiaominting Song, Wenya Yang, Hang You, Shan Qian et autres

Abstract The aryl hydrocarbon receptor (AHR) is a transcription factor prominently expressed at barrier sites, while aldehyde dehydrogenase 3 family member A1 (ALDH3A1) is a metabolic enzyme implicated in oxidative stress. However, their roles in ferroptosis remain poorly understood. Imperatorin (IMP) is …

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Improving the cyclic stability of room-temperature-sputtered WO3 electrochromic film via an in-situ electrical annealing initiated by the intrinsic ITO transparent electrode

Qi Cheng, Ye Yang, Chengzhang Chen, Xinyu Ji et autres

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GJB2 Drives LUAD Progression via cAMP-Mediated M2 Macrophage Polarization through the PKA-CREB Pathway

Yuanhua Liu, Guang‐Hui Liu, Jingjing Mei, Jia Li et autres

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Broadband asymmetric polarization beam splitter with high-extinction ratio using nanopore subwavelength gratings

Shuailong Li, Mingrui Zhang, Qian Meng, Jia Li et autres

We propose a broadband, high-extinction-ratio asymmetric polarization beam splitter based on a nanohole subwavelength grating. By precisely engineering the phase-matching conditions within the coupling region, efficient separation of the TE and TM polarization modes is achieved. Numerical simulation indicates that under TE-mode …

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Halogen-free pyrazine additives enabling nonhalogenated solvent-processed organic solar cells with efficiency over 20%

Yingyi Wang, Jiacheng Xu, Haiyang Chen, Junyuan Ding et autres

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A novel single-vector featuring bidirectional promoters for production of bispecific antibody against rabies virus

Zhigao Zhang, Jia Li, Guanfeng Lin, Shouchun Cao et autres

BACKGROUND: The World Health Organization (WHO) recommends combination therapy with two non-overlapping monoclonal antibodies (mAbs) to enhance protection in Rabies post-exposure prophylaxis (PEP). While bispecific antibodies (bsAbs) provide superior protection over monoclonal antibodies (mAbs) by simultaneously targeting two distinct epitopes, their development …

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Biomimetic Gourd‐Vine Supramolecular Engineering for High‐Performance Organic Cathode Through Dual‐Mode of Anion Coordination and Conjugated Redox Activation

Xianchun Liu, Jian Ku Shang, Yan Cheng, Qingguang Pan et autres

Abstract P‐type organic cathode materials feature multielectron redox activity, structural tunability, and elevated redox potentials, making them promising candidates for battery applications. Nevertheless, their practical deployment remains hindered by inherent challenges, particularly the persistent dissolution issue in conventional electrolytes, leading to rapid …

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Over 26% and 24%-Efficiency Rigid and Flexible Perovskite Photovoltaics through Enhanced Crystallinity and Alleviated Residual Strains

Shuai Gao, Xi Fan, Jinzhao Wang, Wei Feng et autres

The realization of the perovskite with few ionic defects, high crystallinity, and alleviated residual strains is crucial for making efficient rigid and flexible perovskite solar cells (PSCs). Herein, we used a passivating agent of 3-methylthio-1,2,4-triazine with strong anchoring strengths to passivate defects …

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Multichannel Detection of Hybrid Spin‐Orbital Mode Pairs

Rong Yan, Hammad Ahmed, Ruoxing Wang, Chunmei Zhang et autres

Abstract A photon in a vortex beam with a circular polarization state simultaneously carries an orbital angular momentum (OAM) and a spin angular momentum (SAM). A hybrid spin‐orbital mode pair (HSOMP) refers to two beams with opposite topological charges and circular polarization …

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