Qiongqiong Hu

Neural‐Specific Expression and Membrane Localization of FAM163B Regulates SAP97 Expression

Xiaoyu Zhang, Shanshan Sun, Wei Zhao, Yan Jiang et autres

The cell membrane plays a significant role in the development and functional maintenance of neurons. However, the functions of many neuronal membrane proteins remain unclear, posing a challenge to the treatment of brain diseases. Family with sequence similarity 163 member B (FAM163B) …

cn, ru (code pays fourni par la source)

[Neurospecific transmembrane protein 240 colocalizes with peroxisomes and activates Rho GDP dissociation inhibitor β].

Qiongqiong Hu, Wenpei Li, Lixia Xu, Ruilei Guan et autres

OBJECTIVES: To investigate the subcellular localization and biological functions of transmembrane protein 240 (TMEM240). METHODS: experiment, HepG2 and Neuro-2a cells were transfected with plasmids for overexpression of TMEM240, and subcellular localization of TMEM240 was analyzed using cell imaging. In primary cultures of …

cn (code pays fourni par la source)

S100A9 deletion in microglia/macrophages ameliorates brain injury through the STAT6 / PPARγ pathway in ischemic stroke

Xi Liu, Junmin Wang, Jian Jun Jin, Qiongqiong Hu et autres

BACKGROUND: Microglia and infiltrated macrophages (M/M) are integral components of the innate immune system that play a critical role in facilitating brain repair after ischemic stroke (IS) by clearing cell debris. Novel therapeutic strategies for IS therapy involve modulating M/M phenotype shifting. …

cn (code pays fourni par la source)

The neuroprotective effects of normobaric oxygen therapy after stroke

Chuan Li, Min Jiang, Zhiying Chen, Qiongqiong Hu et autres

BACKGROUND: Stroke, including ischemic and hemorrhagic stroke, is a severe and prevalent acute cerebrovascular disease. The development of hypoxia following stroke can trigger a cascade of pathological events, including mitochondrial dysfunction, energy deficiency, oxidative stress, neuroinflammation, and excitotoxicity, all of which are …

cn (code pays fourni par la source)

Immune‐mediated disruption of the blood–brain barrier after intracerebral hemorrhage: Insights and potential therapeutic targets

Peijun Jia, Qinfeng Peng, Xiaochong Fan, Yumeng Zhang et autres

AIMS: Intracerebral hemorrhage (ICH) is a condition that arises due to the rupture of cerebral blood vessels, leading to the flow of blood into the brain tissue. One of the pathological alterations that occurs during an acute ICH is an impairment of …

cn, us, at (code pays fourni par la source)

Neural-specific distribution of transmembrane protein TMEM240 and formation of TMEM240-Body

Qiongqiong Hu, Guangyou Wang, Xin Chen, Liulei Zhang et autres

cn (code pays fourni par la source)

Regulator of G protein signaling 5 (RGS5) inhibits sonic hedgehog function in mouse cortical neurons

Chuanliang Liu, Qiongqiong Hu, Jing Jia, Yun Zhang et autres

cn (code pays fourni par la source)