Cyril Jousse

Unlocking the Microbiome-Metabolome Nexus for Innovative One-Health Solution

Nicolas Creusot, Floriant Bellvert, Samuel Bertrand, Cédric Bertrand et autres

Microbial communities, encompassing a vast taxonomic diversity, are fundamental to ecosystem integrity, biogeochemical cycles, and the health of humans, animals, and plants, along the One Health concept. A major scientific goal is to understand how these complex consortia function, interact, and adapt …

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Author response of: How metabolites and metabolism in aquatic biofilms reveal ecological responses to global change and their interactions. Round#1

Nicolas Creusot, Juliette Tison‐Rosebery, Cédric Hubas, Benjamin Marie et autres

A recommendation of: Nicolas Creusot, Juliette Tison-Rosebery, Cedric Hubas, Benjamin Marie, Joey Allen, Joan Artigas, Simon Colas, Natàlia Corcoll, Caroline Doose, Mélissa Eon, Cyril Jousse, Séverine Le Faucheur, Lorenzo Proia, Mechthild Schmitt-Jansen, Soizic Morin How metabolites and metabolism in aquatic biofilms reveal …

L-serine promotes pro-carcinogenic effects of colibactin-producing E. coli

A. Devaux, Romain Villéger, Gwenaëlle Roche, Binta Diémé et autres

Colonic tissues are abnormally colonized by colibactin-producing Escherichia coli (CoPEC) in colorectal cancer (CRC) patients. CoPECs have been shown to promote colorectal carcinogenesis in several pre-clinical CRC mouse models. Here, we report that CoPEC reprograms the metabolism of colonic epithelial cells in …

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How metabolites and metabolism in aquatic biofilms reveal ecological responses to global change and their interactions

Nicolas Creusot, Juliette Tison‐Rosebery, Cédric Hubas, Benjamin Marie et autres

International audience

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Unraveling the Microbiome-Metabolome Nexus for Innovative One-Health Solution

Nicolas Creusot, Floriant Bellvert, Samuel Bertrand, Cédric Bertrand et autres

Microbial communities, encompassing a vast taxonomic diversity, are fundamental to ecosystem integrity, biogeochemical cycles, and the health of humans, animals, and plants, along the One Health concept. A major scientific goal is to understand how these complex consortia function, interact, and adapt …

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L-serine, a key amino acid involved in the pro-carcinogenic effects of colibactin-producing E. coli

A. Devaux, Gwenaelle Roche, Binta Diémé, Marie Lagrée et autres

International audience

Serine, an amino-acid involved in pro-carcinogenic effects of colibactin-producing Escherichia coli in the colon

A. Devaux, Romain Villéger, Binta Diémé, Marie Lagrée et autres

International audience

NMR metabolite quantification of a synthetic urine sample: an inter-laboratory comparison of processing workflows

Cécile Canlet, Catherine Deborde, Edern Cahoreau, Grégory Da Costa et autres

INTRODUCTION: Absolute quantification of individual metabolites in complex biological samples is crucial in targeted metabolomic profiling. OBJECTIVES: An inter-laboratory test was performed to evaluate the impact of the NMR software, peak-area determination method (integration vs. deconvolution) and operator on quantification trueness and …

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Pro-carcinogenic effects of colibactin-producing E. coli in the colon : implication of serine

A. Devaux, Gwenaelle Roche, Binta Diémé, Marie Lagrée et autres

International audience

Preliminary results of a MetaboHUB 2.0 inter-laboratory test on 1D 1H NMR metabolite quantification of a synthetic urine.

Catherine Deborde, Patrick Giraudeau, Edern Cahoreau, Grégory Da Costa et autres

International audience

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Optimization of metabolome extraction procedures and implementation of a PeakForest database for the identification of microorganisms compounds by LC-HRMS

Wiam Mansouri, Cyril Jousse, Marie Lagrée, Nils Paulhe et autres

International audience

Untargeted metabolomics approach to study polymers biodegradation by Rhodococcus Rhodochrous using LC-HRMS

Binta Diémé, Marie Lagrée, Martin Leremboure, Mounir Traı̈kia et autres

International audience