Jinglan He

Global trends and hotspots of macrophage-related research in intervertebral disc degeneration from 2005 to 2025: a bibliometric and visualized analysis

Muhuan Liu, Jinglan He, Jizhen Zhou

Background: Macrophage-mediated imbalances in the immune microenvironment are critical to the pathogenesis of intervertebral disc degeneration (IVDD). Consequently, targeting macrophage polarization to remodel the degenerative microenvironment and promote tissue repair has emerged as a major research hotspot. However, systematic bibliometric analyses of …

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Identifying clinical features associated with electroconvulsive therapy response in adolescents with major depressive disorder using machine learning

Bingyang Zha, Linjie Li, Jinglan He, Jun Cao et autres

Background: Electroconvulsive therapy (ECT) is an effective treatment for adolescent major depressive disorder (MDD), but its efficacy varies. This study utilized machine learning (ML) to identify baseline clinical factors associated with poor ECT response. Methods: We retrospectively enrolled 503 adolescent MDD patients. …

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Functionally segmented small-diameter vascular grafts with excellent mechanical matchability prepared by emulsion spinning method

Ziru Sun, Enxiang Jiao, Chengchen Deng, Meihong Xu et autres

Impact of parental marital status on self-harm in Chinese primary school students: the mediating role of depression and the moderating effect of classmate relationships

Ming Ai, Xiaoming Xu, Wo Wang, Jianmei Chen et autres

Background: Self-harm is an increasing global public health concern, with a growing prevalence in younger children. This study investigates the associations between parental marital status and self-harm behaviors among primary school students, with a focus on the mediating role of depressive symptoms …

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Temporal Dynamic Changes in Functional Connectivity of Reward Network in Depressed Adolescents and Young Adults with and without Suicidal Attempts

Jun Cao, Xiaorong Chen, Jianmei Chen, Xuemei Li et autres

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Inadequate soft tissue coverage and bone loss/comminution are the typical risk factors of surgical site infection in open fractures of the hand: A nomogram prediction model

Tianyang Jia, Jinglan He, Cunliang Miao, Yubin Long et autres

BACKGROUND: Different from other parts of long bone fractures, surgical site infections (SSI) often occurs in open fractures of the hand (OFH) due to the anatomical characteristics and injury mechanisms. Our aim of the study is to investigate the particular risk factors …

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Personalised graded psychological intervention on negative emotion and quality of life in patients with breast cancer

Xianjie Hao, Yanli Yi, Xian Lin, Jie Li et autres

BACKGROUND: Psychological factors are a risk factor for the incidence of breast cancer and have a significant impact on patient prognosis. OBJECTIVE: The present study aims to investigate the effects of personalised graded psychological intervention on negative emotion and quality of life …

Establishment of an animal model of adjacent segment degeneration after interbody fusion and related experimental studies

Song Chen, Shiqi Suo, Zhitao Xie, Jinglan He et autres

BACKGROUND: Degenerative spine conditions are common and frequent clinical diseases, and adjacent segment disease (ASD) after spinal fusion (SF) is a common complication after spinal fusion (SF). In this study, we established an animal model of ASD after interbody fusion to observe …

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Neural correlates of severity in major depressive disorder: A combined structural and resting-state functional MRI study

Xiaoliu Zhang, Jun Cao, Xiaorong Chen, Qian Huang et autres

Major depressive disorder (MDD) is a disabling and severe psychiatric disorder with high risk of suicide, and adulthood is one of the most probable period for the onset. The neural basis underlying the young adults with MDD remains underexplored. In this study, …

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A propensity score matching study: The prevalence of mental health problems among pregnant women at first antenatal care increased in Chongqing during the first wave of the COVID-19 pandemic

Jiamei Guo, Xiao Li, Jinglan He, Ming Ai et autres

Background The 2019 coronavirus disease (COVID-19) pandemic increased the risks of mental health challenges, especially anxiety and depression. However, the impact of COVID-19 on mental health during pregnancy has not been fully established. Therefore, we investigated the impact of the COVID-19 pandemic …

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Severity related neuroanatomical and spontaneous functional activity alteration in adolescents with major depressive disorder

Xiaoliu Zhang, Jun Cao, Qian Huang, Hong Su et autres

Background: Major depressive disorder (MDD) is a disabling and severe psychiatric disorder with a high rate of prevalence, and adolescence is one of the most probable periods for the first onset. The neurobiological mechanism underlying the adolescent MDD remains unexplored. Methods: In …

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Prospective study on Maresin-1 and cytokine levels in medication-naïve adolescents with first-episode major depressive disorder

Tian Qiu, Xiao Li, Wanjun Chen, Jinglan He et autres

Background: Inflammation and immune activation may play a role in the pathological mechanism of Major Depressive Disorder (MDD). Evidence from cross-sectional and longitudinal studies of adolescents and adults has shown that MDD is associated with increased plasma pro-inflammatory cytokines (e.g., IL-1β, IL-6). …

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