Xiaoliang Zhao

Biomimetic self-assembled microspheres based on selenized Angelica-Astragalus compound polysaccharides and platelet membranes for targeted therapy of acute liver injury

Xiaoliang Zhao, Hanwen Zhang, Doudou Ma, Jiandong Ma et autres

Abstract Liver injury remains a major clinical challenge due to the limited bioavailability and potential immunogenicity of conventional therapeutics. Microspheres derived from traditional Chinese medicine (TCM) polysaccharides have attracted increasing attention owing to their biocompatibility and immunoregulatory activities. However, most conventional delivery …

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Coherence analysis of peripheral blood flow signals is a potential method for evaluating autonomic nervous system function

Qiuyue Lyu, Xin Wang, Qizhen Wang, Qi Liu et autres

Introduction: The autonomic nervous system (ANS) is crucial for maintaining homeostasis in the body and plays an important role in cardiovascular diseases. Although heart rate variability (HRV) is a commonly used non-invasive clinical tool to evaluate the function of ANS, it mainly …

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Corrigendum to “Dual-crosslinked Cirsiumsetosum polysaccharide/quaternary chitosan self-healing hydrogel promotes wound healing” [Carbohydrate Research 556 2025 109616]

Li Ma, Liyuan Lu, Xiaoliang Zhao, Qingsong Zhou et autres

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Dual-crosslinked cirsiumsetosum polysaccharide/quaternary chitosan self-healing hydrogel promotes wound healing

Li Ma, Liyuan Lu, Xiaoliang Zhao, Qingsong Zhou et autres

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Preparation, Structure Characteristics, Antioxidant, Antitumor, and Immunomodulatory Activity of Polysaccharides From Rheum officinale Baill. and Their Derivatives

Xiaoliang Zhao, Yanmei Liu, Haili Wang, Karen Qi et autres

In this study, three polysaccharides (RHC, RHH, and RHA) were sequentially extracted from Rheum officinale Baill., under different conditions, and their sulfated, phosphorylated, and selenated derivatives were successfully synthesized. Results indicated that the sequential extraction method effectively separated polysaccharides with distinct structures. …

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Sulfated modification of polysaccharides from Sophora flavescens: Impact on antioxidant, antitumor, and immunomodulatory activities

Xiaoliang Zhao, Qingsong Zhou, Haijin Mou, Li Ma et autres

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High-sensitivity detection of tetracycline using phosphorus-doped carbon quantum dots prepared by pyrolysis method as fluorescent probes

Cunjin Wang, Zixin Ma, Yao Zhuoru, Peipei Li et autres

Abstract The selective and highly sensitive detection of trace tetracycline antibiotic residues is crucial for ensuring food safety and maintaining organismal health. In the present study, we describe a novel method for tetracycline detection utilizing phosphorus-doped carbon quantum dots (P-CQDs) synthesized via …

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Preparation of pH-Sensitive Astragalus Polysaccharide Nanoparticles Loaded with Paclitaxel and Evaluation of Antitumor Activity

Kaibin Wang, Yanqiang Li, Xiaoliang Zhao, Tianke Zhu et autres

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Electrochemical study of oxidized hyaluronic acid grafted with aniline tetramer Bletilla striata polysaccharide hydrogel wound dressings

Xiaofei Wang, Xiaoliang Zhao, Yonggang Wang, Jing Zhang et autres

Bletilla striata polysaccharide, also known as Bletilla gum, is a water-soluble polymeric viscous polysaccharide with antimicrobial and coagulation-promoting activities. This study used Bletilla striata polysaccharide as the base material and crosslinked it with an electroactive carrier material to prepare a hydrogel with …

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[Aqueous extract of Chuan Xiong Rhizoma enhances inhibitory effect of temozolomide against brain metastasis of melanoma in mice].

Qihong Zhao, Zhenfeng Zhang, X Zhou, Xiaocui Rong et autres

OBJECTIVE: To investigate the effect of the aqueous extract of Chuan Xiong Rhizoma (CR) on brain metastasis of melanoma B16F10 cells in mice. METHODS: imaging. RESULTS: CR-treated mouse models did not show obvious progression of brain metastases and had a reduced rate …

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The Polysaccharides from Pinellia ternata and Their Derivatives: Preparation, Structure Characteristics, and Activities in Vitro

Xiaoliang Zhao, Zheng‐lei Guo, Kai‐li Qi, Qingsong Zhou et autres

Abstract Three polysaccharides, PTC, PTH, and PTB, were extracted from Pinellia ternata using three different extraction conditions: room temperature water, hot water, and 2 % Na2CO3 solution. PTC and PTH were composed of rhamnose, glucose, galactose, mannose, glucuronic acid, galacturonic acid, and …

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Accelerated self-assembly of filipin proteins and formation of hydrogels

Xiaoliang Zhao, Chuanhui Zhang, Pingping Li, Liyuan Lu et autres

This study delineates the novel revelation that traditional Chinese medicine polysaccharides facilitate and expedite the intramolecular conformational alterations within filipin proteins, culminating in amplified β-fold content and self-assembly proclivity to generate hydrogels. Augmentation of assembly kinetics was achieved by pH or ethanol …

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