Jonas Meisner

A generative model for dimensionality reduction with millions of features and few samples

Corrado Pancotti, Piero Fariselli, Jonas Meisner, Anders Krogh

Abstract Motivation In this paper, we demonstrate that it is feasible to train a deep generative model for dimensionality reduction with millions of features using few samples, which makes this type of generative model a more versatile alternative to standard methods for …

de, it, dk (code pays fourni par la source)

Faroese whole genomes provide insight into ancestry and recent selection

Iman Hamid, Ólavur Mortensen, Alba Refoyo-Martínez, Leivur N. Lydersen et autres

Abstract The Faroe Islands are home to descendants of a North Atlantic founder population with a unique history shaped by both migration and periods of relative isolation. Here, we investigate the genetic diversity, population structure, and demographic history of the islands by …

us, fo, dk (code pays fourni par la source)

Reviewer #1 (Public review): Faroese Whole Genomes Provide Insight into Ancestry and Recent Selection

Iman Hamid, Ólavur Mortensen, Alba Refoyo-Martínez, Leivur N Lydersen et autres

The Faroe Islands are home to descendants of a North Atlantic founder population with a unique history shaped by both migration and periods of relative isolation. Here, we investigate the genetic diversity, population structure, and demographic history of the islands by analyzing …

Author response: Faroese Whole Genomes Provide Insight into Ancestry and Recent Selection

Iman Hamid, Ólavur Mortensen, Alba Refoyo-Martínez, Leivur N Lydersen et autres

The Faroe Islands are home to descendants of a North Atlantic founder population with a unique history shaped by both migration and periods of relative isolation. Here, we investigate the genetic diversity, population structure, and demographic history of the islands by analyzing …

Reviewer #2 (Public review): Faroese Whole Genomes Provide Insight into Ancestry and Recent Selection

Iman Hamid, Ólavur Mortensen, Alba Refoyo-Martínez, Leivur N Lydersen et autres

The Faroe Islands are home to descendants of a North Atlantic founder population with a unique history shaped by both migration and periods of relative isolation. Here, we investigate the genetic diversity, population structure, and demographic history of the islands by analyzing …

Faroese Whole Genomes Provide Insight into Ancestry and Recent Selection

Iman Hamid, Ólavur Mortensen, Alba Refoyo-Martínez, Leivur N. Lydersen et autres

The Faroe Islands are home to descendants of a North Atlantic founder population with a unique history shaped by both migration and periods of relative isolation. Here, we investigate the genetic diversity, population structure, and demographic history of the islands by analyzing …

ch, us, fo, dk (code pays fourni par la source)

Accurate and scalable genome-wide ancestry estimation using haplotype clusters

Jonas Meisner

Unsupervised genome-wide ancestry estimation in unrelated individuals has been a staple in population and medical genetics for decades, and its importance continues to grow with the increasing number of large genetic cohorts of mixed ancestries. We propose an extension to the hapla …

dk (code pays fourni par la source)

Complex genetic effects linked to plasma protein abundance in the UK Biobank

Arnór I. Sigurdsson, Justus F. Gräf, Zhiyu Yang, Kirstine Ravn et autres

Understanding genetic associations of proteins is important for studying the molecular effect of genetic variation. A key component of this is to understand the role of complex genetic effects such as dominance and epistasis that are associated with plasma proteins. Therefore, we …

us, dk, fi, de, gb (code pays fourni par la source)

The genetic diversity of Indonesian cattle has been shaped by multiple introductions and adaptive introgression

Casia Nursyifa, Sabhrina Gita Aninta, Genís Garcia‐Erill, Laura D. Bertola et autres

Genetic diversity is a crucial resource in livestock, determining their traits and ability to respond to selection. Indonesian cattle are unique due to their history of admixture involving both zebu (Bos indicus) and banteng (B. javanicus), and may therefore contain novel cattle …

dk, in, au, id, np, cn, nl, us, gb, de (code pays fourni par la source)

Accurate and scalable genome-wide ancestry estimation using haplotype clusters

Jonas Meisner

Abstract Unsupervised genome-wide ancestry estimation has been a staple in population and medical genetics for decades, and its importance continues to grow with the increasing number of large genetic cohorts of mixed ancestries. We propose an extension to the hapla framework that …

dk (code pays fourni par la source)

Faroese Whole Genomes Provide Insight into Ancestry and Recent Selection

Iman Hamid, Ólavur Mortensen, Alba Refoyo-Martínez, Leivur N. Lydersen et autres

Abstract The Faroe Islands are home to descendants of a North Atlantic founder population with a unique history shaped by both migration and periods of relative isolation. Here, we investigate the genetic diversity, population structure, and demographic history of the islands by …

ch, us, fo, dk (code pays fourni par la source)

Faroese whole genomes provide insight into ancestry and recent selection

Iman Hamid, Ólavur Mortensen, Alba Refoyo-Martínez, Leivur N. Lydersen et autres

The Faroe Islands are home to descendants of a North Atlantic founder population with a unique history shaped by both migration and periods of relative isolation. Here, we investigate the genetic diversity, population structure, and demographic history of the islands by analyzing …

ch, us, fo, dk (code pays fourni par la source)