Da-Yu Zhu

Proanthocyanidins induce analgesic and anxiolytic effects in spared nerve injured mice by decreasing in vivo firing rate of pyramidal cells in the insular cortex

Pan Wang, Hua-Xing Si, Da-Yu Zhu, Ke-Ke Xing et autres

Neuropathic pain is one of the most common symptoms of clinical pain that often accompanied by severe emotional changes such as anxiety. However, the treatment for comorbidity of chronic pain and anxiety is limited. Proanthocyanidins (PACs), a group of polyphenols enriched in …

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Glutamatergic synapses from the insular cortex to the basolateral amygdala encode observational pain

Mingming Zhang, Anqi Geng, Kun Chen, Jian Wang et autres

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Proanthocyanidins Inhibit the Transmission of Spinal Pain Information Through a Presynaptic Mechanism in a Mouse Inflammatory Pain Model

Hongwei Fan, Zhen-Yu Wu, Da-Yu Zhu, Junxiang Gu et autres

Inflammatory pain is one of the most common symptoms of clinical pain that seriously affects patient quality of life, but it currently has limited therapeutic options. Proanthocyanidins, a group of polyphenols enriched in plants and foods, have been reported to exert anti-inflammatory …

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The increased in vivo firing of pyramidal cells but not interneurons in the anterior cingulate cortex after neuropathic pain

Da-Yu Zhu, Tingting Cao, Hongwei Fan, Mingzhe Zhang et autres

Chronic pain damages the balance between excitation and inhibition in the sensory cortex. It has been confirmed that the activity of cortical glutamatergic pyramidal cells increases after chronic pain. However, whether the activity of inhibitory interneurons synchronized changed remains obscure, especially in …

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The Increased In Vivo Firing of Pyramidal Cells But not Interneurons in the Anterior Cingulate Cortex After Neuropathic Pain

Da-Yu Zhu, Tingting Cao, Hongwei Fan, Mingzhe Zhang et autres

Abstract Chronic pain damages the balance between excitation and inhibition in the sensory cortex. It has been confirmed that the activity of cortical glutamatergic pyramidal cells increases after chronic pain. However, whether the activity of inhibitory interneurons synchronized changed remains obscure, especially …

cn (code pays fourni par la source)