Ying-Ying Goh

The ratio between SARS-CoV-2 RNA viral load and culturable viral titre differs depending on the stage of infection: a case study of household transmission in an adult male

Michael K. Porter, Alexander Viloria Winnett, Linhui Hao, Natasha Shelby et autres

Effective public health measures for communicable diseases rely on the ability to identify infectious individuals and prevent transmission from those individuals. For severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the presence of replication-competent virus in specimens from an individual is the gold …

us (code pays fourni par la source)

Wildfires and health: building resilience in Los Angeles’ climate crisis

Ying-Ying Goh, Y. Tony Yang

us (code pays fourni par la source)

The ratio between SARS-CoV-2 RNA viral load and culturable viral titer differs depending on stage of infection: case study of household transmission in an adult male

Michael K. Porter, Alexander Viloria Winnett, Linhui Hao, Natasha Shelby et autres

Effective public health measures for communicable diseases rely on the ability to identify infectious individuals and prevent transmission from those individuals. For SARS-CoV-2, the presence of replication-competent virus in specimens from an individual is the gold standard for confirming infectiousness. However, viral …

us, in (code pays fourni par la source)

Notes from the Field: First Locally Acquired Dengue Virus Infections — Pasadena, California, October–December 2023

Matthew Feaster, Rudy Patrick, M. Oshiro, M.-M. Kuan et autres

This information was current when accessed October 2, 2023.In 2023, the recommended radius was 0.16 miles (250 meters); however, in 2024, the recommended radius is 0.09 miles (150 meters).

us (code pays fourni par la source)

The ratio between SARS-CoV-2 RNA viral load and culturable viral titer differs depending on stage of infection

Michael K. Porter, Alexander Viloria Winnett, Linhui Hao, Natasha Shelby et autres

Analysis of incident, longitudinal RNA viral loads in saliva and nasal swabs and culturable viral titers in nasal swabs collected twice-daily by a tricenarian male infected with SARS-CoV-2 revealed the ratio between viral load and viral titer can be five orders of …

us, in (code pays fourni par la source)

Index cases first identified by nasal-swab rapid COVID-19 tests had more transmission to household contacts than cases identified by other test types

Jenny Ji, Alexander Viloria Winnett, Natasha Shelby, Jessica A. Reyes et autres

At-home rapid COVID-19 tests in the U.S. utilize nasal-swab specimens and require high viral loads to reliably give positive results. Longitudinal studies from the onset of infection have found infectious virus can present in oral specimens days before nasal. Detection and initiation …

us (code pays fourni par la source)

The ratio between SARS-CoV-2 RNA viral load and culturable viral titer differs depending on stage of infection

Michael Porter, Alexander Viloria Winnett, Linhui Hao, Natasha Shelby et autres

Abstract Analysis of incident, longitudinal RNA viral loads in saliva and nasal swabs and culturable viral titers in nasal swabs collected twice-daily by a tricenarian male infected with SARS-CoV-2 revealed the ratio between viral load and viral titer can be five orders …

us (code pays fourni par la source)

Daily SARS-CoV-2 Nasal Antigen Tests Miss Infected and Presumably Infectious People Due to Viral Load Differences among Specimen Types

Alexander Viloria Winnett, Reid Akana, Natasha Shelby, Hannah Davich et autres

We reveal three findings from a longitudinal study of daily nasal antigen rapid diagnostic test (Ag-RDT) evaluated against SARS-CoV-2 viral load quantification in three specimen types (saliva, nasal swab, and throat swab) in participants enrolled at the incidence of infection. First, the …

us (code pays fourni par la source)

Index Cases First Identified by Nasal-Swab Rapid COVID-19 Tests Had More Transmission to Household Contacts Than Cases Identified by Other Test Types

Jenny Ji, Alexander Viloria Winnett, Natasha Shelby, Jessica A. Reyes et autres

ABSTRACT Importance At-home rapid COVID-19 tests utilize nasal-swab specimens and require high viral loads to reliably give positive results. Longitudinal studies from the onset of infection have found infectious virus can present in oral specimens days before nasal. Detection and initiation of …

us (code pays fourni par la source)

Extreme differences in SARS-CoV-2 viral loads among respiratory specimen types during presumed pre-infectious and infectious periods

Alexander Viloria Winnett, Reid Akana, Natasha Shelby, Hannah Davich et autres

Abstract SARS-CoV-2 viral-load measurements from a single-specimen type are used to establish diagnostic strategies, interpret clinical-trial results for vaccines and therapeutics, model viral transmission, and understand virus–host interactions. However, measurements from a single-specimen type are implicitly assumed to be representative of other …

us (code pays fourni par la source)

Morning SARS-CoV-2 Testing Yields Better Detection of Infection Due to Higher Viral Loads in Saliva and Nasal Swabs upon Waking

Alexander Viloria Winnett, Michael K. Porter, Anna E. Romano, Emily S. Savela et autres

Our findings suggest that collecting saliva and nasal swab specimens in the morning immediately after waking yields higher SARS-CoV-2 viral loads than collection later in the day. The higher viral loads from morning specimen collection are predicted to significantly improve detection of …

us (code pays fourni par la source)

Extreme differences in SARS-CoV-2 viral loads among respiratory specimen types during presumed pre-infectious and infectious periods

Alexander Viloria Winnett, Reid Akana, Natasha Shelby, Hannah Davich et autres

ABSTRACT SARS-CoV-2 viral load measurements from a single specimen type are used to establish diagnostic strategies, interpret clinical-trial results for vaccines and therapeutics, model viral transmission, and understand virus-host interactions. However, measurements from a single specimen type are implicitly assumed to be …

us (code pays fourni par la source)