Begimai Akbalaeva

The Joint Role of Serum Markers of Congestion or Myocardial Necrosis And Speckle Tracking Echocardiography in The Detection of Early Subtle Chemotherapy-Induced Cardiotoxicity in Women With Breast Cancer

N. Raiimbek uulu, И В Першуков, L. V. Shulzhenko, Begimai Akbalaeva et autres

Aim To monitor the dynamics of biomarkers during chemotherapy, targeted chemotherapy and targeted monotherapy in patients with HER2-positive breast cancer (BC); to analyze the emergence timing of these changes; to compare early biochemical and echocardiographic criteria; and to determine the best time …

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Comparative Analysis of Speckle-Tracking Echocardiography and Cardio-Specific Markers for Early Detection of Cardiotoxicity in Patients with Breast Cancer

Begimai Akbalaeva, Salman Khan, Priti B. Singh, Mukhtar Ansari et autres

Objectives: Breast cancer (BC) treatment often involves cardiotoxic chemotherapy, leading to potential cardiac dysfunction. Early detection of cardiotoxicity is crucial for timely intervention and improved patient outcomes. This study aims to compare the effectiveness of speckle-tracking echocardiography (STE) and cardiospecific markers in …

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Age‐Related Long‐Term Longitudinal Changes in Left Ventricular Mechanical Function in Breast Cancer Patients Undergoing Anthracycline and Trastuzumab Treatment

Begimai Akbalaeva, Priti Singh, Salman Khan

Age significantly influences the severity of chemotherapy-induced cardiotoxicity (cardiotoxicity) in HER2-positive breast cancer patients. Comprehensive cardiac monitoring before, during, and after anthracycline and trastuzumab regimens is essential. Tailored assessments can help identify vulnerable patients, optimize treatment, and mitigate risks of heart complications …

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Speckle-tracking echocardiography: a tool for early detection of cardiotoxicity in cancer patients after chemotherapy

Begimai Akbalaeva, N. Raiimbek uulu, Isabek Gulamov, Kuttubek T. Abylov et autres

In modern oncology, despite the efficacy of chemotherapy, there is a risk of cardiotoxicity resulting in heart failure. This necessitates early diagnosis to prevent complications and improve prognosis. The study is aimed at analysing the abilities of speckle-tracking echocardiography as a modern …

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Echo-loop of subclinical cardiovascular toxicity in women associated with HER2-positive breast cancer therapy

И В Першуков, Begimai Akbalaeva, L. V. Shulzhenko, Batyraliev Ta et autres

Aim. To assess the incidence and timing of subclinical cardiac dysfunction associated with therapy for HER2-positive locally advanced or metastatic breast cancer, and to analyze the difference in time from significant reduction in left ventricular (LV) global longitudinal strain (GLS) to significant …

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Speckle-Tracking Echocardiography in Assessment of Breast Cancer Therapy-Related Subclinical Cardiac Dysfunction

Begimai Akbalaeva, L. V. Shulzhenko, И В Першуков, N. Raiimbek uulu et autres

Background: Cancer therapy-related cardiac dysfunction (CTRCD) is a new term that encompasses a wide range of potential manifestations and is etiologically associated with a wide variety of cancer treatments. Detection of early subclinical cardiac dysfunction is of great clinical importance. Objective: To …

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The Clinical Evolution of Diffuse Myocardial Fibrosis in Patients With Arterial Hypertension and Heart Failure With Mildly Reduced Ejection Fraction Treated by Olmesartan or Sacubitril / Valsartan

L. V. Shulzhenko, И В Першуков, Batyraliev Ta, Zarema Karben et autres

Aim A 12-month evaluation of the potentialities of the angiotensin II receptor inhibitor olmesartan (Olme) and the angiotensin receptor and neprilysin inhibitor (ARNI) sacubitril/valsartan in patients with arterial hypertension (AH) and dyslipidemia in the dynamics of the following indicators of chronic heart …

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CASE REPORT: BRUGADA- LIKE ECG PATTERN IN PATIENT AFTER SUCH AS LONG-TERM OUTCOME OF COVID-19

Begimai Akbalaeva, Hingmire Omkar Chandrakant, Sabirakhan Mamatova, Batyraliev Ta et autres

This article presents a clinical case of a patient who developed a Brugada-like electrocardiogram (ECG) pattern as a delayed complication after recovering from COVID-19. Brugada syndrome is a rare genetic disorder characterized by abnormal changes on the ECG and an increased risk …

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Focus on Cardiotoxicity and Its Prevention in Patients With Cancer Diseases

Begimai Akbalaeva, Batyraliev Ta, M. Tursunbaev, Роман Калматов et autres

Research relevance: currently, in many less developed countries, including Kyrgyzstan, cardioprotection has not previously been performed in cancer patients receiving chemotherapy, which should be given special attention. If patient has a pre-existing cardiovascular disease, then the heart disease should first be corrected …

[Ischemic Heart Disease: Focus on Acute Infarction of the Right Ventricular Myocardium].

Begimai Akbalaeva, Batyraliev Ta, D V Fettzer, Б А Сидоренко

Ischemic heart disease and acute myocardial infarction (AMI) in particular remain widely spread and contribute seriously in total mortality of population. This literature review is devoted to the right ventricular (RV) AMI as the least studied problem of contemporary cardiology. We present …

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