Becky Leung

Pre-transplant azacitidine does not improve survival in allogeneic HSCT for higher-risk MDS

Miles Horton, Becky Leung, Ricky Nelles, Matthew Rubic et autres

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Real World Outcomes of Ruxolitinib Treatment of Steroid Refractory/Dependent Acute Graft Versus Host Disease

Becky Leung, Jason Butler, Cameron Curley, Andrea Henden et autres

Aim: Steroid-refractory and/or dependent acute graft versus host disease (SR/SD-aGVHD) is a life-threatening complication following allogeneic haematopoietic stem cell transplantation (HSCT). The REACH-2 study established ruxolitinib as standard of care compared to historical salvage options, however patients with lower gastrointestinal (GI) involvement …

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Prior Azacitidine and Ongoing Transfusion Dependence in MDS Patients Are Associated with Inferior Survival after Allogeneic Stem Cell Transplant

Miles Horton, Becky Leung, Ricky Nelles, Matthew Rubic et autres

Background: Allogeneic stem cell transplantation (alloSCT) remains the only curative therapy for myelodysplastic syndromes (MDS). Outcomes in alloSCT for MDS are often pooled with AML, making the interpretation of risk factors and application to clinical practice challenging. Prior studies have demonstrated impact …

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Analytical Validation of a 37-Gene Next-Generation Sequencing Panel for Myeloid Malignancies and Review of Initial Findings Incorporating Updated 2022 Diagnostic and Prognostic Guidelines

Becky Leung, Hnin Hnin Aung, Adayapalam Nandini, Ghusoon Abdulrasool et autres

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Treatment of multiple synchronous canine mast cell tumours using intratumoural tigilanol tiglate

Graham Brown, Jessica R. Finlay, Rodney C. Straw, Joy Y. Ziea et autres

Mast cell tumours (MCTs) are common canine skin neoplasia. While they generally occur as single tumours, multiple synchronous MCTs (msMCTs) of de novo/non-metastatic origin are reported in a proportion of the patient population. Where there is no evidence of metastasis or lymphatic …

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Fibrinogen Longmont: A Clinically Heterogeneous Dysfibrinogenemia with Discrepant Fibrinogen Results Influenced by Clot Detection Method and Reagent

Becky Leung, Joanne Beggs, Jane Mason

Fibrinogen is a 340 kDa glycoprotein composed of three pairs of polypeptide chains. Thrombin cleaves the N-terminal Aα and Bβ chains, exposing binding sites that enable polymerization and cross-linking to form a fibrin clot. Fibrinogen disorders can be quantitative or qualitative, inherited …

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P28.02 Beyond PACIFIC: Outcomes and Toxicity According to Durvalumab Dosing Schedule Every 2 versus 4 Weeks

Marie-Hélène Denault, Shelley Kuang, Ali Shokoohi, Becky Leung et autres

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Two cases of differentiation syndrome with ocular manifestations in patients with acute promyelocytic leukaemia treated with all-trans retinoic acid and arsenic trioxide

Alexander R. Newman, Becky Leung, Angela Richards, Thomas G. Campbell et autres

PURPOSE: To describe two cases of differentiation syndrome presenting with ocular manifestations including bilateral chorioretinopathy in patients with acute promyelocytic leukaemia treated with all-trans retinoic acid and arsenic trioxide differentiation therapy. OBSERVATIONS: This observational case series identifies two patients at a single …

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Response to Letter to the Editor: ‘Cardiovascular risk profile in burn survivors: Methodological issues’

Becky Leung, J. Younger, Kellie Stockton, Michael Müller et autres

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Cardiovascular risk profile in burn survivors

Becky Leung, J. Younger, Kellie Stockton, Michael Müller et autres

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Risks of Gestational Diabetes and Preeclampsia Over the Last Decade in a Cohort of Alberta Women

Kara Nerenberg, Jeffrey Johnson, Becky Leung, Anamaria Savu et autres

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Model-based etch profile simulation of PSM films

Michael Grimbergen, Madhavi Chandrachood, Jeffrey Tran, Becky Leung et autres

For advanced binary and PSM mask etch, final profile control is critically important for achieving desired mask specifications. As an aid to attain profile control, an etch profile simulation method has been developed. The method starts with an initial photoresist profile and …

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