Accès ouvert
2026
article
OpenAlex
Chee Kiang Ewe, Hanna Achache, Hanna Schön, Leonid Kontorovich et autres
Thermal pollution, whether local or driven by global warming, threatens biodiversity in part through its detrimental effects on reproduction. Non-coding small RNAs (sRNAs) are crucial for maintaining germline developmental robustness under heat stress. Remarkably, we uncovered that neuronal sRNAs regulate germ cells' …
il, at
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2026
article
OpenAlex
Priti Agarwal, Iska Maimon Zielonka, Hila Gingold, Victor Stolzenbach et autres
Collective cell invasion underlies organ development, epithelial repair, and cancer metastasis. "Leader cells" remodel ECM, sense guidance cues, reorganize their cytoskeleton, and coordinate follower cells, but the molecular programs enabling these functions remain unclear. Here, we present a stage-specific transcriptomic dataset of …
at, il, us
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Accès ouvert
2026
preprint
OpenAlex
Prakash Varkey Cherian, Idit Aviram, Uri Weill, Tamar Shapira et autres
Summary How cells and organisms preserve molecular memory is a central question in biology. Chromatin states can maintain cellular memory in animals, yet DNA and histone modifications are typically reset in the germ line and early embryo. In Caenorhabditis elegans , RNA-dependent …
il, de
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Accès ouvert
2026
preprint
OpenAlex
Itai Rieger, Yael Mor, Itamar Lev, Anat Nitzan et autres
Abstract Temporary disruptions to epigenetic mechanisms can misroute development and permanently alter cell fate. In particular, it was recently shown that transient loss of Polycomb silencing in flies irreversibly reprograms cells toward cancer (Parreno et al. 2024). Whether somatic dysfunction in parents …
il
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Accès ouvert
2026
article
OpenAlex
Thomas Lemberger, Niv Mastboim, Oded Rechavi
A survey of researchers who compared AI-generated scientific reviews with journal-agnostic human peer review reveals that they overwhelmingly prefer using AI as a self-checking tool before submission rather than as a replacement for human reviewers. It encourages an “author-centric” model in which …
de, il
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2026
other
OpenAlex
Oded Rechavi
In my talk I will discuss recent work from my lab about transgenerational epigenetic inheritance, showing how, at least in nematodes, experiences can be transmitted across generations through small RNAs, altering behavior and physiology in descendants. I will connect these findings to …
il
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Accès ouvert
2025
article
OpenAlex
Dana Landschaft-Berliner, Kesem Goldstein, Guy Teichman, Sarit Anava et autres
The persistence of memory reflects not only how it is formed but also how forgetting is delayed. The mechanisms controlling forgetting remain obscure, and in particular it is unclear to what degree this process is actively regulated. We discovered that cold exposure …
il, in, es
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Accès ouvert
2025
preprint
OpenAlex
Priti Agarwal, Hila Gingold, Victor Stolzenbach, Sarit Anava et autres
Abstract Collective cell invasion underlies organ development, epithelial repair, and cancer metastasis. “Leader cells” remodel extracellular matrix, sense guidance cues, reorganize their cytoskeleton, and coordinate follower cells, but the molecular programs enabling these functions remain unclear. Here, we present a stage-specific transcriptomic …
in, il, us, mx
(code pays fourni par la source)
Accès ouvert
2025
preprint
OpenAlex
Chee Kiang Ewe, Hanna Achache, Shir Weiss, Anna Mogilevskaya et autres
Abstract Thermal pollution, whether local or driven by global warming, threatens biodiversity in part through its detrimental effects on reproduction. Non-coding small RNAs (sRNAs) are crucial for maintaining germline developmental robustness under heat stress. Remarkably, we uncovered that neuronal sRNAs regulate germ …
il, in
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Chee Kiang Ewe, Guy Teichman, Oded Rechavi
mutants lacked a consistent pattern, suggesting IIS may regulate RNAi components via post-translational mechanisms.
il
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Accès ouvert
2025
article
OpenAlex
Chee Kiang Ewe, Guy Teichman, Shir Weiss, Maximilian M. L. Knott et autres
Small RNAs (sRNAs), coupled with Argonaute proteins (AGOs), regulate diverse biological processes, including immunity against nucleic acid parasites. C. elegans possesses an expanded repertoire of at least 19 AGOs functioning in an intricate gene regulatory network (GRN). However, the regulation of AGOs …
il, us
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Accès ouvert
2024
preprint
OpenAlex
Peter Szanto, David H. Meyer, Mélanie Bazin-Gelis, Thanh Vuong-Brender et autres
Transposable elements (TEs) can alter genome structure through transposition, and their activity is therefore tightly restricted by small RNA-mediated and chromatin-based silencing mechanisms. In C. elegans , elevated temperature can induce TE expression, raising the question of whether thermosensory neurons influence TE …
de, il
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