Jun‐Kai Kao

Knowledge, attitudes, and practices toward food allergies among early childhood educators in Taiwan: a cross-sectional study

Fang-Ting Lu, Chien-Che Ting, Kan-Hsuan Lin, Cheng-Han Lee et autres

AbstractBackground: The prevalence of food allergies among Taiwanese children has risen to 10.4%, which is notably higher than that in many other Asian regions. However, despite this trend, Taiwan lacks specialized legislation or standardized national protocols for the management of food allergies …

Knowledge, attitudes, and practices toward food allergies among early childhood educators in Taiwan: a cross-sectional study

Fang-Ting Lu, Chien-Che Ting, Kan-Hsuan Lin, Cheng-Han Lee et autres

AbstractBackground: The prevalence of food allergies among Taiwanese children has risen to 10.4%, which is notably higher than that in many other Asian regions. However, despite this trend, Taiwan lacks specialized legislation or standardized national protocols for the management of food allergies …

Knowledge, attitudes, and practices toward food allergies among early childhood educators in Taiwan: a cross-sectional study

Fang-Ting Lu, Chien-Che Ting, Kan-Hsuan Lin, Cheng-Han Lee et autres

BACKGROUND: The prevalence of food allergies among Taiwanese children has risen to 10.4%, which is notably higher than that in many other Asian regions. However, despite this trend, Taiwan lacks specialized legislation or standardized national protocols for the management of food allergies …

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CARD8 variant-mediated inflammasome activation in a case of refractory Behçet disease: from PFAPA to atypical neurovascular involvement

Yu-Hsuan Pai, Kan-Hsuan Lin, Shun-Cheng Yang, Chien‐Sheng Hsu et autres

Dear Editor, Behçet’s disease (BD) is a multisystem inflammatory disorder characterized by chronic vasculitis. The clinical presentation of paediatric Behçet’s disease (pBD) markedly differs from that of adult-onset disease [1]. Although HLA-B51 remains the primary genetic risk factor, recent evidence indicates that …

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Regulatory B cell expansion and type 1 innate lymphoid cell suppression characterise immune modulation in paediatric lupus nephritis

Ching-Yuang Lin, Jien‐Wen Chien, Kan-Hsuan Lin, Kai-Hung Hsiao et autres

Objective B-cell activating factor (BAFF) is essential for B-cell survival and innate immune activation, and its dysregulation contributes to the pathogenesis of lupus nephritis (LN). This study investigated whether BAFF-pathway inhibition alters the balance between regulatory B cells (Bregs) and type 1 …

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Low hyper-oxygen exposure induces p21-dependent p53-independent senescence in alveolar cells

Cheng-Han Lee, Kan-Hsuan Lin, Ming-Sheng Lee, Chao-Jen Lin et autres

Bronchopulmonary dysplasia (BPD) is a chronic pulmonary condition predominantly affecting premature neonates who necessitate oxygen therapy. Currently, BPD is classified into two types-old and new BPD-that differ in histology and pathology. The new BPD is observed in premature infants exposed to gentle …

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Non-Transferrin-Bound Iron Drives Ferroptosis in THP-1 derived Macrophages via Heme oxygenase-1 Pathway

Shih-Chung Wang, Cheng-Han Lee, Kan-Hsuan Lin, Rei-Cheng Yang et autres

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The role of P30 adhesin detected by ultrasensitive ELISA in the clinical diagnosis and management of Mycoplasma pneumoniae

Po-Kai Chen, Kan-Hsuan Lin, Guan‐Ming Ke, Shun‐Cheng Yang et autres

BACKGROUND: Mycoplasma pneumoniae (MP) is a common cause of pediatric respiratory infections, but its diagnosis remains challenging due to nonspecific clinical features and the limitations of conventional laboratory tests. METHODS: We evaluated the diagnostic and clinical utility of P30 detection using the …

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The differences of clinical features and neutrophils’ stress between IL-17 positive and negative patients of type 1 diabetes mellitus

Kan-Hsuan Lin, Yi‐Lei Wu, Chin-Hui Tseng, Yi‐Giien Tsai et autres

BACKGROUND: Type 1 diabetes mellitus (T1D) is an autoimmune disorder characterized by immune-mediated destruction of pancreatic β-cells, resulting in lifelong insulin dependence. Interleukin-17A (IL-17A), associated with T1D progression and complications, can mobilize and activate neutrophils to release lytic enzymes, reactive oxygen species, …

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Impact of sleep disturbance on mental health in schoolchildren with atopic dermatitis: A population-based study

Kan-Hsuan Lin, Yu‐Jun Chang, Tung‐Ming Chang, Kuender D. Yang et autres

Objective: This Taiwanese population-based cross-sectional (CARE) study examined associations between sleep disturbances and mental health symptoms in adolescents with atopic dermatitis (AD). Method: A cross-sectional analysis was conducted among 14,675 adolescents (median age: 12.6 years; 49.7% male) using validated self-report questionnaires to …

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Lipopolysaccharide‐Induced Lysosomal Cell Death Through Reactive Oxygen Species in Rat Liver Cell Clone 9

Chien‐Sheng Hsu, Shu‐Hao Chang, Rei‐Cheng Yang, Cheng‐Han Lee et autres

In sepsis, bacterial components, particularly lipopolysaccharide (LPS), trigger organ injuries such as liver dysfunction. Although sepsis induces hepatocyte damage, the mechanisms underlying sepsis-related hepatic failure remain unclear. In this study, we demonstrated that the LPS-treated rat hepatocyte cell line Clone 9 not …

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Low-dose imiquimod induces melanogenesis in melanoma cells through an ROS-mediated pathway

Zhengyi Li, Shu-Hao Chang, Kuang-Ting Liu, Alaina Edelie Wu et autres

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