CaBagE: a Cas9-based Background Elimination strategy for targeted, long-read DNA sequencing
Amelia D. Wallace, Thomas A. Sasani, Jordan Swanier, Brooke L. Gates et autres
Abstract A substantial fraction of the human genome is difficult to interrogate with short-read DNA sequencing technologies due to paralogy, complex haplotype structures, or tandem repeats. Long-read sequencing technologies, such as Oxford Nanopore’s MinION, enable direct measurement of complex loci without introducing …
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