Wenmei Zeng

Clinical utility of the targeted next-generation sequencing for detection of Mycoplasma pneumoniae and antimicrobial resistance genes for adults

Long Yuan, Zhuofan Liu, Wenmei Zeng, Zie Zhan et autres

BACKGROUND: Mycoplasma pneumoniae pneumonia (MPP) is common in children, and its incidence among adolescents and adults has been increasing in recent years. Targeted next-generation sequencing (tNGS) is a rapid, accurate and comprehensive method for pathogen detection; however, few studies have investigated its …

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Hypoxic Burden and T90% as Predictive Indicators of Cardiovascular Risk and Myocardial Ischemia in Patients with Obstructive Sleep Apnea

Wenmei Zeng, Sulong Wu, Z Liu, Long Yuan et autres

Purpose: This study analyzed the role of hypoxic burden and the percentage of time with blood oxygen saturation below 90% (T90%) in assessing the myocardial ischemia and cardiovascular risk in obstructive sleep apnea (OSA) patients using portable sleep monitors. Patients and Methods: …

Screening and early diagnosis of chronic obstructive pulmonary disease: a population study

Wenhui Tang, Rong Yan, Hongmei Zhang, Wenji Lin et autres

BACKGROUND AND OBJECTIVE: Although chronic obstructive pulmonary disease (COPD) is a common disease leading to further morbidity and significant mortality, there is still limited data on screening for COPD. The purpose of this study was to establish an early chronic obstructive pulmonary …

Mechanical Stress and the Induction of Lung Fibrosis via the Midkine Signaling Pathway

Rong Zhang, Ying‐Xian Pan, Vito Fanelli, Sulong Wu et autres

RATIONALE: Lung-protective ventilatory strategies have been widely used in patients with acute respiratory distress syndrome (ARDS), but the ARDS mortality rate remains unacceptably high and there is no proven pharmacologic therapy. OBJECTIVES: Mechanical ventilation can induce oxidative stress and lung fibrosis, which …

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