Seok Hoo Jeong

Analysis of Helium Monte Carlo Data for the ISS-CREAM Instrument

Arvind Bagga, Sandeep Aggarwal, Y. Amare, D. Angelaszek et autres

The Role of Mammalian Target of Rapamycin (mTOR) and Adenosine Monophosphate-Activated Protein Kinase (AMPK) Signaling in Skeletal Muscle Hypertrophy: A Literature Review With Implications for Health and Disease

Seok Hoo Jeong

Maintaining skeletal muscle mass is fundamental not only for strength and mobility but also for metabolic health, disease prevention, and healthy aging. Skeletal muscle functions as a dynamic metabolic organ, and its maintenance depends on the delicate equilibrium between mammalian target of …

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Regulation of senescence-associated secretory phenotypes in osteoarthritis by cytosolic UDP-GlcNAc retention and O-GlcNAcylation

Donghyun Kang, Jeeyeon Lee, Geunho Yook, Seok Hoo Jeong et autres

UDP-GlcNAc serves as a building block for glycosaminoglycan (GAG) chains in cartilage proteoglycans and simultaneously acts as a substrate for O-GlcNAcylation. Here, we show that transporters for UDP-GlcNAc to the endoplasmic reticulum (ER) and Golgi are significantly downregulated in osteoarthritic cartilage, leading …

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A159 SERUM IGG RESPONSE TO THE D0-D1 HINGE PEPTIDE OF COMMENSAL FLAGELLIN PREDICTS THE FUTURE ONSET OF CROHN’S DISEASE IN HEALTHY FIRST-DEGREE RELATIVES

Richard Wu, Meilan Xue, Qi Zhao, Seok Hoo Jeong et autres

Abstract Background Elevated antimicrobial antibody levels have been reported up to 6 years before diagnosis of Crohn’s disease (CD), but the specific antibody response is poorly defined. Aims Here, we characterized the nature of the antimicrobial antibody responses before the diagnosis of …

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Mass composition of ultrahigh energy cosmic rays from distribution of their arrival directions with the Telescope Array

Rashid Abbasi, Yasuaki Abe, T. Abu-Zayyad, M. Allen et autres

We use a new method to estimate the injected mass composition of ultrahigh cosmic rays (UHECRs) at energies higher than 10 EeV. The method is based on comparison of the energy-dependent distribution of cosmic ray arrival directions as measured by the Telescope …

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The cosmic ray energetics and mass for the international space station (ISS-CREAM) instrument

Y. S. Yoon, Y. Amare, D. Angelaszek, N Anthony et autres

The ISS-CREAM instrument is the modified version of the Cosmic Ray Energetics And Mass (CREAM) experiment, which was flown on balloons multiple times over Antarctica and later installed on the International Space Station (ISS). Its primary objective is to measure the energy …

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Oral Sulfate Solution Is as Effective as Polyethylene Glycol with Ascorbic Acid in a Split Method for Bowel Preparation in Patients with Inactive Ulcerative Colitis: A Randomized, Multicenter, and Single-Blind Clinical Trial

Ji Min Lee, Kang‐Moon Lee, Ho Suk Kang, Ja Seol Koo et autres

Background/Aims: Low-volume preparations for colonoscopy are gaining attention for their higher acceptability. However, the efficacy and safety of oral sulfate solution (OSS) preparations in patients with ulcerative colitis (UC) has not been well known. Therefore, we aimed to compare OSS and 2-L …

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Results from the Cosmic Ray Energetics And Mass for the International Space Station (ISS-CREAM) experiment

E. S. Seo, S. Aggarwal, Y. Amare, D. Angelaszek et autres

The Cosmic Ray Energetics And Mass for the International Space Station (ISS-CREAM) experiment took high-energy cosmic ray data for 539 days after its successful installation on the ISS in August 2017. The ISS-CREAM instrument is configured with complementary particle detectors capable of …

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Clinical Features of Intra-Abdominal Abscess and Intestinal Free-Wall Perforation in Korean Patients with Crohn’s Disease: Results from the CONNECT Study

Seok Hoo Jeong, Ja Sung Choi, Jin-Woo Kim, Hee Man Kim et autres

Background: In Crohn’s disease (CD), intra-abdominal abscess (IA) and intestinal free-wall perforation (IP) have a common mechanism of transmural inflammation; however, their manifestation is different. Objective: This study aimed to investigate differences in the clinical features between IA and IP in Korean …

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The Association between Nonalcoholic Fatty Liver Disease and Stroke: Results from the Korean Genome and Epidemiology Study (KoGES)

Yun-Jung Yang, Mi‐Hyang Jung, Seok Hoo Jeong, Yeon‐Pyo Hong et autres

(1) Background: Non-alcoholic fatty liver disease (NAFLD) is associated with various cardiometabolic diseases. However, the association between NAFLD and stroke is not well known. The purpose of our study is to reveal the relationship between NAFLD and Stroke incidence. (2) Methods: Using …

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Upregulation of Peroxiredoxin-2 in Well-Differentiated Pancreatic Neuroendocrine Tumors and Its Utility as a Biomarker for Predicting the Response to Everolimus

Eui Joo Kim, Yoon Jae Kim, Hye In Lee, Seok Hoo Jeong et autres

Pancreatic neuroendocrine neoplasms (pNENs) account for 2-3% of pancreatic malignancies. Peroxiredoxins (Prdxs), which are major cellular antioxidants, are involved in multiple oncogenic signaling pathways. We investigated the role of peroxiredoxin-2 in QGP-1 human pNEN cell line and patient-derived pNEN tissue. To validate …

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NRF2 Knockdown Resensitizes 5-Fluorouracil-Resistant Pancreatic Cancer Cells by Suppressing HO-1 and ABCG2 Expression

Eui Joo Kim, Yoon Jae Kim, Hye In Lee, Seok Hoo Jeong et autres

Chemoresistance is a leading cause of morbidity and mortality in patients with pancreatic cancer and remains an obstacle to successful treatment. The antioxidant transcription factor nuclear factor (erythroid-derived 2)-related factor 2 (NRF2), which plays important roles in tumor angiogenesis and invasiveness, is …

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