Aela A. Williams

W31. KETAMINE AND ELECTROCONVULSIVE THERAPY DEPRESSION TREATMENTS ALTER ISOFORM- AND CELL TYPE-SPECIFIC TRANSCRIPTOMES IN THE MOUSE PREFRONTAL FRONTAL CORTEX

Samar Nasser Chehimi, Richard C. Crist, Alexander I. Batterman, Aela A. Williams et autres

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Widening the Opioid Analgesia Therapeutic Window with a Dual Pharmacology Strategy

Indu Mithra Madhuranthakam, Sarah Uribe, Danya Aldaghma, Drew T. Kwitchoff et autres

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Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C disease

Sarah Kim, Kathleen Ochoa, Sierra E. Melli, Fawad A. K. Yousufzai et autres

Abstract Purkinje cell (PC) loss occurs at an early age in patients and animal models of Niemann-Pick Type C (NPC), a lysosomal storage disease caused by mutations in the Npc1 or Npc2 genes. Although degeneration of PCs occurs early in NPC, little …

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Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C disease

Sarah Kim, Kathleen Ochoa, Sierra E. Melli, Fawad A. K. Yousufzai et autres

Abstract Purkinje cell (PC) loss occurs at an early age in patients and animal models of Niemann-Pick Type C (NPC), a lysosomal storage disease caused by mutations in the Npc1 or Npc2 genes. Degeneration of PCs occurs early in NPC, however little …

us, pr (code pays fourni par la source)