Fiona Larsen

A finding of granuloma faciale associated with basal cell carcinoma

Loebat Kamalpour, Bryan Gammon, Fiona Larsen, Robert E. Cashman et autres

The clinical differential diagnosis of violaceous plaques on the face is broad and includes both neoplasms and inflammatory dermatoses. We report the first case of a basal cell carcinoma (BCC) superficial to an underlying granuloma faciale (GF). This is a single case …

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Verrucous linear (segmental) psoriasis of the right leg responding to radiation therapy.

Fiona Larsen, Alan Menter, Clay J. Cockerell, Barry N. Wilcox

Verrucous linear segmental psoriasis (VLSP) is invariably recalcitrant to treatment. It is a distinct variant of psoriasis that frequently is considered a form of a verrucous linear, epidermal nevus. The hypertrophic nature of the plaques makes treatment particularly challenging. The authors present …

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Development of new-onset psoriasis in a patient receiving infliximab for treatment of rheumatoid arthritis

Chung-Yin Stanley Chan, John Browning, Fiona Larsen, Sylvia Hsu

Infliximab is a chimeric monoclonal antibody that selectively blocks tumor necrosis factor-alpha (TNF-alpha). It is indicated for the treatment of numerous inflammatory diseases, including rheumatoid arthritis, Crohn disease, ulcerative colitis, ankylosing spondyilitis, and psoriatic arthritis. Infliximab has also been shown to be …

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Congenital Atrophic Dermatofibrosarcoma Protuberans in a 7‐Month‐Old Boy Treated with Mohs Micrographic Surgery

Jamison D. Feramisco, Fiona Larsen, SARAH B. WEITZUL, Clay J. Cockerell et autres

Dermatofibrosarcoma protuberans is a rare, malignant, slow-growing, locally invasive tumor of the skin. Although most cases are acquired and diagnosed in adulthood, there have been an increasing number of congenital dermatofibrosarcoma protuberans mimicking benign birthmarks described in the literature. The clinical presentation …

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Leprosy

Fiona Larsen, Arlo Upton, Johannes Stricker, Clay J. Cockerell

EPIDEMIOLOGY Leprosy is an ancient disease that has been the cause of great morbidity and mortality for centuries. The causative agent, Mycobacterium leprae , is an unculturable, obligate intracellular, gram-positive, acid-fast bacillus. It multiplies very slowly in the host and grows best …

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The Dysplastic Nevus Concept

Fiona Larsen, Clay J. Cockerell

“Dysplastic” nevi (DN), also known as Clark's nevi, are lesions that have characteristic clinical and histologic features that may be a marker for increased melanoma risk in some individuals. The magnitude of the risk of melanoma in patients with DN is dependent …

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Special Site Nevi in Pregnancy

Fiona Larsen, Molly J. Burns, Clay J. Cockerell

Nevi of special sites occur on genital, breast, flexural, and acral skin. Lesions at these locations have distinctive histologic features and display both architectural and cytologic atypia. They can simulate dysplastic nevi or melanoma and therefore cause diagnostic concern. Rarely, pregnancy can …

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Case of multiple verrucous carcinomas responding to treatment with acetretin more likely to have been a case of verrucous psoriasis

Fiona Larsen, Joseph S Susa, Clay J. Cockerell, William Abramovits

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Cutis verticis gyrata: Three cases with different aetiologies that demonstrate the classification system

Fiona Larsen, Nicholas M. Birchall

Cutis verticis gyrata describes a scalp condition where there are convoluted folds and deep furrows that resemble the surface of the cerebral cortex. We report three cases of cutis verticis gyrata that demonstrate the current classification structure. The first case is the …

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Education together with a preprinted sticker improves the prescribing of prophylactic enoxaparin.

Patrick A. Gladding, Fiona Larsen, Hilary Durrant, Peter Black

INTRODUCTION: Substantial evidence exists for the use of prophylactic heparin in medical inpatients with congestive heart failure and severe respiratory disease, and in surgical patients with a moderate-to-high risk of thromboembolism (Grade 1A recommendations). Despite this, many patients who would benefit from …

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