Elpis Mantadakis

Pediatric Oral Iron Therapy: Choosing the Right Product for Your Patient

Sonia Alexiadou, Emmanouela Tsouvala, Elpis Mantadakis

In this narrative review, we address the prevention and therapy of iron deficiency anemia (IDA) with oral iron products in pediatric patients. Fortification of complementary foods with iron-containing micronutrient powders is the preferred method for the prevention of IDA in resource-limited settings. …

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Pediatric Oral Iron Therapy: Choosing the Right Product for Your Patient

Sonia Alexiadou, Emmanouela Tsouvala, Elpis Mantadakis

In this narrative review, we address the prevention and therapy of iron deficiency anemia (IDA) with oral iron products in pediatric patients. Fortification of complementary foods with iron-containing micronutrient powders is the preferred method for the prevention of IDA in resource-limited settings. …

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An update in the diagnosis and therapy of hemophagocytic lymphohistiocytosis

Elpis Mantadakis, Sonia Alexiadou

Primary hemophagocytic lymphohistiocytosis (pHLH) is a fatal, autosomal recessive hyperinflammatory syndrome. Infections, neoplasia, and underlying autoimmune and autoinflammatory conditions trigger secondary HLH. In pHLH, immunosuppression with dexamethasone and etoposide has been used as the standard of care before hematopoietic transplantation, the only …

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Relapsing Salmonella Meningitis in an Infant: A Case Report and Review of the Literature

Sonia Alexiadou, Elpis Mantadakis, Ioanna Irakleidou, Stavroula Kalatzi et autres

Accurate diagnosis of bacterial meningitis is critical, particularly in young febrile infants. Although commercially available multiplex PCR assays enable rapid pathogen detection, these typically do not include Salmonella spp. or other Enterobacteriaceae, which may result in missed diagnoses and/or inappropriate treatment duration. …

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Therapeutic Approaches in Children with Invasive Meningococcal Disease (IMD) in Greece.

Panagiotis Poulikakos, Dimitrios Kapnisis, Despοina Gkentzi, Μαρία Τσολιά et autres

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Vitamin D Intoxication Caused by a Manufacturing Error in a Prescribed Vitamin D3 Supplement, Successfully Managed with Low-Dose Zoledronic Acid

Sonia Alexiadou, Stavros Thomaidis, Anna Papazoglou, Anastasia Grapsa et autres

We describe a male toddler with a history of operated posterior urethral valves who developed vitamin D toxicity with hypercalcemia after he was prescribed orally 6,000 IU of cholecalciferol daily for two months for vitamin D deficiency. The disordered calcium metabolism was …

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Invasive Meningococcal Disease in Children: Outcomes and Risk Factors for Sequelae and Fatal Cases in Greece

Panagiotis Poulikakos, Dimitrios Kapnisis, Athanasia Xirogianni, Irini Liakou et autres

Invasive meningococcal disease (IMD) remains a major public health challenge due to its rapid progression, which may lead to severe sequelae or death in children and adolescents. Published data on IMD sequelae are limited in Greece and many EU countries. In the …

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Emergency Identification of Endotracheal Tube Tip via Ultrasonography Used by Trained Nurse in the Neonatal Intensive Care Unit (NICU)

Athanasia Voulgaridou, Savas Deftereos, Pelagia Chloropoulou, Konstantina Bekiaridou et autres

Background: Endotracheal tube (ETT) placement is crucial for neonates with respiratory failure. Ultrasonography (US) has emerged as a valuable tool to detect ETT positioning, competing with traditional methods. Nurses, being front-line caregivers, can perform basic ultrasound examinations. This study aimed to assess …

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Serious Accidental Poisoning Due to Consumption of Cassia Occidentalis Seeds in A 3-Year-Old Girl from Greece

Serafeia Kalamitsou, Stavros Thomaidis, Vasiliki Avramidou, Maria Terzidou et autres

The authors describe a 3-year-old previously healthy girl who presented with new-onset hepatic encephalopathy due to accidental consumption of Cassia occidentalis seeds. The child found the seeds four days before her presentation in the dehiscent fruits of a plant that was kept …

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The Effect of Ferric Carboxymaltose on Fibroblast Growth Factor 23 (FGF23) in Children with Iron Deficiency Anemia Due to Gastrointestinal Diseases

Maria Ntoumpara, Elpis Mantadakis, Lemonia Skoura, Paraskevi Panagopoulou et autres

Background: Hypophosphatemia is a known side-effect of parenteral iron administration, especially after intravenous ferric carboxymaltose (FCM). Fibroblast growth factor 23 (FGF23) is thought to play an important role in the pathophysiology of serum phosphate homeostasis. This study aimed to investigate the effects …

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ORAL IRON-HYDROXIDE POLYMALTOSE COMPLEX VERSUS SUCROSOMIAL IRON FOR CHILDREN WITH IRON DEFICIENCY WITH OR WITHOUT ANEMIA: A CLINICAL TRIAL WITH EMPHASIS ON INTESTINAL INFLAMMATION

Sonia Alexiadou, Christina Tsigalou, Εleni Kourkouni, Aggelos Tsalkidis et autres

Background: Iron deficiency anemia (IDA) is a major public health problem among children worldwide. Iron deficiency without anemia (IDWA) is at least twice as common as IDA. Some studies propose that oral iron fortification can modify the infant's gut microbiome, leading to …

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Transfusion-related acute lung injury/transfusion-associated circulatory overload in a child with non-transfusion dependent thalassemia and aplastic crisis due to acute parvovirus B19 infection

Elpis Mantadakis, Angeliki Vittoraki, Alexandra Siorenta, Eftychia Kontekaki

We present a never-transfused girl with thalassemia intermedia who was admitted for febrile aplastic crisis due to human parvovirus B19. After a first transfusion of packed red blood cells, she developed pulmonary oedema. She improved with supportive care including the use of …

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