Shawn S. Jackson

Adherence to Sedation Protocol Recommendations in Intubated ICU Patients

Taylor M. Smith, Caroline Pane, Soseh Hovasapian, Franklin Ducatez et autres

OBJECTIVES: Sedation in critically ill children is a complex challenge. Both inadequate sedation and oversedation are undesirable and carry consequences. Standardized sedation protocols aim to reduce practice variability, minimize drug exposure, and improve outcomes. Although widely used, adherence to sedation protocols remains …

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Cumulative exposure to opioids and benzodiazepines in extremely preterm neonates

Michael William Kuzniewicz, Lena S. Sun, Shawn S. Jackson, J. Madison Davis

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Cumulative Exposure to Opioids and Benzodiazepines in Extremely Preterm Neonates

Michael William Kuzniewicz, Lena S. Sun, Shawn S. Jackson, Jonathan W. Davis

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Peri-Operative Care of Technology-Dependent Adolescents and Young Adults

Jia Liu, Robert J. Graham, Shawn S. Jackson

Caring for technology-dependent adolescents and young adults presents significant challenges, especially for procedural and peri-operative care. This review delves into the complexities of managing these patients before, during, and after major medical procedures or operations, highlighting the unique medical and psychosocial issues …

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The Use of Real-world Data to Generate Real-world Evidence to Accelerate Neonatal Drug Development

Shawn S. Jackson, Joseph P. Cravero, Lena S. Sun, J. Madison Davis

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Sedation Strategies in Pediatric Intensive Care Unit Patients: Challenges in Management

Shawn S. Jackson, Teeda Pinyavat, Hülya Bayır, Heidi A. B. Smith

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Use of Sedative and Analgesic Agents in Pediatric Intensive Care Unit Patients: Pediatric Health Information System Database

Jennifer Lee, Ann Kim, Shawn S. Jackson

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Potential consequences of nitric oxide release: An improved model informing worker safety

Gautham Venugopalan, Rocco J. Casagrande, Noah Gunther, Rashmi Prasad et autres

Abstract Both nitric oxide (NO) and nitrogen dioxide (NO2) gasses are toxic to humans but are commonly found in industrial settings such as semiconductor manufacturing sites. Due to the spontaneous oxidation of NO to NO2 under ambient conditions, individuals working with NO …

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Sedation Research in Critically Ill Pediatric Patients: Proposals for Future Study Design From the Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research IV Workshop

Shawn S. Jackson, Jennifer Lee, William M. Jackson, Jerri C. Price et autres

OBJECTIVES: Sedation and analgesia for infants and children requiring mechanical ventilation in the PICU is uniquely challenging due to the wide spectrum of ages, developmental stages, and pathophysiological processes encountered. Studies evaluating the safety and efficacy of sedative and analgesic management in …

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National Survey of Combined Pediatrics-Anesthesiology Residents and Graduates: Factors Contributing to Changing Career Aspirations Over Time

Jia Liu, Shawn S. Jackson, James Xie, Matthew J. Rowland et autres

BACKGROUND: The Dual Pathway for Certification in Pediatrics and Anesthesiology was created in 2011 to develop leaders in caring for children with complex medical and surgical conditions. While existing dual-trained practitioners report continued practice in both pediatric anesthesiology (PA) and pediatric critical …

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Reply to: Democratizing biotechnology requires more than availability

Shawn S. Jackson, Louise E. Sumner, Rocco J. Casagrande

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A 35-Year Review of Pre-Clinical HIV Therapeutics Research Reported by NIH ChemDB: Influences of Target Discoveries, Drug Approvals and Research Funding.

Shawn S. Jackson, Louise E. Sumner, Mikaela Finnegan, Emily A. Billings et autres

We present a retrospective analysis of trends in human immunodeficiency virus (HIV) small molecule drug development over the last thirty-five years based on data captured by ChemDB, a United States (US) National Institutes of Health (NIH) database of chemical and biological HIV …

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