Jane Bowles

Ultradian hydrocortisone replacement alters neuronal processing, emotional ambiguity, affect and fatigue in adrenal insufficiency: The PULSES trial

Georgina Russell, Konstantinos Kalafatakis, Claire Durant, Nicola Marchant et autres

BACKGROUND: Primary adrenal insufficiency (PAI) mortality and morbidity remain unacceptably high, possibly arising as glucocorticoid replacement does not replicate natural physiology. A pulsatile subcutaneous pump can closely replicate cortisol's circadian and ultradian rhythm. OBJECTIVES: To assess the effect of pump therapy on …

gb, gr, mt, ch, au (code pays fourni par la source)

X Chromosome Contribution to the Genetic Architecture of Primary Biliary Cholangitis

Rosanna Asselta, Elvezia Maria Paraboschi, Alessio Gerussi, Heather J. Cordell et autres

it, gb, jp, cn, ca, us (code pays fourni par la source)

Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score

Marco Carbone, Alessandra Nardi, Steve Flack, Guido Carpino et autres

gb, it (code pays fourni par la source)

International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

Heather J. Cordell, Younghun Han, George Mells, Yafang Li et autres

Primary biliary cirrhosis (PBC) is a classical autoimmune liver disease for which effective immunomodulatory therapy is lacking. Here we perform meta-analyses of discovery data sets from genome-wide association studies of European subjects (n=2,764 cases and 10,475 controls) followed by validation genotyping in …

gb, us, ca, it, de, pl, cn, lt (code pays fourni par la source)

Listeria meningitis and resultant symptomatic hydrocephalus complicating infliximab treatment for ulcerative colitis

Fahd Rana, Muddassir Shaikh, Jane Bowles

Listeria monocytogenes, an uncommon pathogen, should be considered by clinicians as a source of sepsis and meningitis in the immunocompromised individuals, including those on anti-TNF alpha agents. Immunosuppressant agents including biologic therapies have transformed the management of various rheumatological and dermatological conditions.(1) …

gb (code pays fourni par la source)

P544 Bone mineral density measurement using dual energy X-ray in inflammatory bowel disease patients – Are we screening our patients for osteoporosis?

Faisal Rana, David J. Tate, Muddassir Shaikh, Jane Bowles

F.A. Rana, D. Tate, M.M. Shaikh, J. Bowles; P544 Bone mineral density measurement using dual energy X-ray in inflammatory bowel disease patients – Are we s