Profil bibliographique

Marissa K. Cooper

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

3Publications signalées

66Citations signalées

2Affiliations récentes

Les institutions déclarées

Harvard University Massachusetts General Hospital

Les domaines associés

Hemoglobinopathies and Related DisordersErythrocyte Function and PathophysiologyMitochondrial Function and PathologyMetabolism and Genetic DisordersNeonatal Health and Biochemistry

Les publications récentes

Accès ouvert 2022 article OpenAlex

High-Throughput Assay to Screen Small Molecules for Their Ability to Prevent Sickling of Red Blood Cells

Akito Nakagawa, Marissa K. Cooper, Maria Kost‐Alimova, James Berstler et autres

High Resolution Image Download MS PowerPoint Slide Sickle cell disease (SCD) is an inherited disorder of hemoglobin (Hb); approximately 300,000 babies are born worldwide with SCD each year. In SCD, fibers of polymerized sickle Hb (HbS) form in red blood cells (RBCs), …

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9 citations ACS Omega

Accès ouvert 2021 article OpenAlex

Hypoxia ameliorates brain hyperoxia and NAD+ deficiency in a murine model of Leigh syndrome

Robert M. H. Grange, Rohit Sharma, Hardik Shah, Bryn Reinstadler et autres

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31 citations Molecular Genetics and Metabolism

Accès ouvert 2018 article OpenAlex

A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells

Akito Nakagawa, Michele Ferrari, Grigorij Schleifer, Marissa K. Cooper et autres

Abstract Sickle cell disease is an inherited disorder of hemoglobin (Hb). During a sickle cell crisis, deoxygenated sickle hemoglobin (deoxyHbS) polymerizes to form fibers in red blood cells (RBCs), causing the cells to adopt “sickled” shapes. Using small molecules to increase the …

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26 citations Molecular Pharmaceutics

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