Yingjie Bai

Low-pH-induced conformational changes in the spike protein promote porcine deltacoronavirus infection by enhancing viral binding efficiency to the porcine aminopeptidase receptor

Ruiming Yu, Liping Zhang, Peng Zhou, Zhongwang Zhang et autres

ABSTRACT Porcine deltacoronavirus (PDCoV) is a critical enteric pathogen causing severe diarrhea in neonatal piglets, with fecal-oral transmission as its primary route. However, the molecular mechanism underlying PDCoV adaptation to the acidic gastric environment of hosts remains elusive. Here, we demonstrate that …

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Gut microbiota alters drug metabolism and therapeutic outcomes

Guo F, Yingjie Bai, Xiaoguang Lei

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Immune responses triggered by oral administration of recombinant Bacillus subtilis expressing the E2 protein of classical swine fever virus

Yongcong Zhao, Zhongyuan Ma, Zhongwang Zhang, Jianliang Lv et autres

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Development of an S protein-based indirect ELISA for detecting IgA antibodies against porcine deltacoronavirus

Zhiming Zhao, Ruiming Yu, Jing Dai, Peng Zhou et autres

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Indirect ELISA based on truncated N protein for detecting Porcine deltacoronavirus-specific IgA antibodies

Dongsheng Wang, Liping Zhang, Ruiming Yu, Zhongwang Zhang et autres

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Pseudopaline-mediated zinc uptake by Pseudomonas aeruginosa drives clinically relevant phenotypes and infection outcomes

Lola Bosc, Thomas Sécher, Geneviève Ball, Déborah Le Pennec et autres

ABSTRACT Biological metals are vital trace elements required by metalloproteins, which are involved in virtually every cellular, structural, and catalytic function of the bacterial cell. Bacterial pathogenesis involves a tug-of-war between the host’s nutritional immunity sequestering essential metals and the invading pathogens …

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A colloidal gold immunochromatographic test strip based on mAbs anti-S protein to detect porcine deltacoronavirus

Ya Liu, Yingjie Bai, Liping Zhang, Ruiming Yu et autres

Porcine deltacoronavirus (PDCoV), an important porcine enteric coronavirus, poses a serious threat to the swine industry. Effective prevention and control require early diagnosis and detection. Previously developed colloidal gold immunochromatographic test strips targeted nucleocapsid protein. However, several studies have reported cross-reactivity between …

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[A truncated N protein-based ELISA method for the detection of antibodies against porcine deltacoronavirus].

Dongsheng Wang, Ruiming Yu, Yingjie Bai, Xia Liu et autres

This study aims to establish an antibody detection method for porcine deltacoronavirus (PDCoV). The recombinant proteins PDCoV-N1 and PDCoV-N2 were expressed via the prokaryotic plasmid pColdII harboring the N gene sequence of the PDCoV strain CH/XJYN/2016. The reactivity and specificity of PDCoV-N1 …

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A Study on Airport Runway Detection Based on an Improved YOLOv11 Algorithm

Yingjie Bai, Shaoqing Xu, Xiaoyue Liu, Xiaowen Su

With the development of remote sensing technology and artificial intelligence, automatic detection of airport runways has important application value in aviation safety, drone navigation, and other fields. Addressing the issues of low detection accuracy and insufficient feature extraction in traditional target detection …

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Research on Airport Runway Detection Method based on Improved YOLOv11

Xiaowen Su, Shaoqing Xu, Yiqing Ren, Yingjie Bai

With the increasing degree of airport automation, higher accuracy and real-time requirements have been put forward for the automatic detection of airport runways, signs, and key targets. In this paper, an airport runway detection method based on improved YOLOv11 is proposed to …

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A study of airport and runway detection based on improved RT-DETR

Xiaoxu Song, Yingjie Bai, Zhang Li, Yifan Li

Aiming at the detection problems of airports and runways in remote sensing images, such as large scale differences and insignificant target features, this paper proposes a target detection method based on improved RT-DETR. First, based on the original architecture of RT-DETR, the …

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Structural Basis for Inhibition of Urate Reabsorption in URAT1

Junping Fan, Wenjun Xie, Han Ke, Jing Zhang et autres

The urate transporter 1 (URAT1) is the primary urate transporter in the kidney responsible for urate reabsorption and, therefore, is crucial for urate homeostasis. Hyperuricemia causes the common human disease gout and other pathological consequences. Inhibition of urate reabsorption through URAT1 has …

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