Veronica Luiza Vale Euclydes

MicroRNA-coordinated synergism for placental gene regulation throughout pregnancy

C. Braga, Gisele Rodrigues Gouveia, Rayssa M.M.W. Feitosa, Caroline Camilo et autres

The regulation of gene expression by microRNAs (miRNAs) is essential during development. However, it is necessary to move beyond individual miRNAs to understand their functions and the intricate interplay as a coordinated system. To address this, we developed and implemented a network …

br, ca (code pays fourni par la source)

Child Neurodevelopment at 36 Months of Age: The Role Early Life Adversities Analysis

Alexandra Brentani, Tiago Choi, Veronica Luiza Vale Euclydes, Helena Brentani

Early life adversities (ELAs) represent a major public health concern due to their long-term consequences for clinical and developmental outcomes (1). Understanding how ELAs shape child development is essential for informing effective prevention and intervention strategies aimed at improving both individual and …

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Role of maternal immune response and placental exosomes in infant cognitive outcome at 12 months of age.

Gisele Rodrigues Gouveia, Caroline Camilo, Sérgio Nery Simões, C. Braga et autres

br, us (code pays fourni par la source)

Placenta vascular alterations and inflammatory lesions associated with placental expression of proteins are related to maternal-fetal nutrients signaling and exposure to glucocorticoids

Gisele Rodrigues Gouveia, Caroline Camilo, Luana Martos Vieira, Veronica Luiza Vale Euclydes et autres

br (code pays fourni par la source)

Development of a placental inflammation index as a biological proxy of gestational stress and intrauterine adversity

Caroline Camilo, Gisele Rodrigues Gouveia, Luana Martos Vieira, Veronica Luiza Vale Euclydes et autres

br (code pays fourni par la source)

Identifying biomarkers and trajectories of executive functions and language development in the first 3 years of life: Design, methods, and findings of the Germina cohort study

Daniel Fatori, Elizabeth A. Shephard, Danilo Benette, Nathalia Ferrazzo Naspolini et autres

Abstract This paper reports the methods and preliminary findings of Germina, an ongoing cohort study to identify biomarkers and trajectories of executive functions and language development in the first 3 years of life. 557 mother-infant dyads (mean age of mothers 33.7 years, …

br, jp, fr (code pays fourni par la source)

A Preliminary Investigation of Associations Between Traumatic Events Experienced During Pregnancy and Salivary Diurnal Cortisol Levels of Brazilian Adolescent Mothers and Infants

Kyle S. Wiley, Gisele Rodrigues Gouveia, Caroline Camilo, Veronica Luiza Vale Euclydes et autres

INTRODUCTION: Interpersonal violence against women is a major global health problem that may have intergenerational effects. This study investigated associations between maternal experiences of interpersonal violence and other traumatic events and maternal and infant salivary diurnal cortisol in a cohort of adolescent …

us, br (code pays fourni par la source)

Innovative approach for the qualitative–quantitative assessment of neurodevelopment biomarkers research in placenta tissue using immunohistochemistry digital image analysis

Caroline Camilo, Luana Martos Vieira, Gisele Rodrigues Gouveia, Arleti Caramori Torrezan et autres

Abstract We aimed to develop and validate a standardized, qualitative–quantitative protocol for digital IHC analysis to assess neurodevelopmental biomarkers in placental tissue. Placental tissues from 60 births were obtained from the Western Region Birth Cohort (ROC), and IHC staining was performed using …

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Maternal immune response during pregnancy and neurodevelopmental outcomes: A longitudinal approach

Veronica Luiza Vale Euclydes, C. Braga, Gisele Rodrigues Gouveia, Raquel Chacon Ruiz Martinez et autres

Background and objectives: The neurodevelopment of the offspring is suggested to be influenced by the maternal immune system's responses throughout pregnancy, which in turn is also vulnerable to maternal psychosocial stress conditions. Therefore, our main goal was to investigate whether maternal peripheral …

br (code pays fourni par la source)

Identifying biomarkers and trajectories of executive functions and language development in the first 3 years of life: design, methods and initial findings of the Germina cohort study

Daniel Fatori, Elizabeth A. Shephard, Nathalia Ferrazzo Naspolini, Grover Enrique Castro Guzmán et autres

This paper reports the methods and preliminary findings of Germina, an ongoing cohort study to identify biomarkers and trajectories of executive functions and language development in the first 3 years of life. 557 mother-infant dyads (mean age of mothers 33.7 years, 65.2% …

br, mx, jp, fr (code pays fourni par la source)

Human archetypal pluripotent stem cells differentiate into trophoblast stem cells via endogenous BMP5/7 induction without transitioning through naive state

Ethan Tietze, Amilton de Lima Barbosa, Bruno Henrique Silva Araújo, Veronica Luiza Vale Euclydes et autres

Primary human trophoblast stem cells (TSCs) and TSCs derived from human pluripotent stem cells (hPSCs) can potentially model placental processes in vitro. Yet, the pluripotent states and factors involved in the differentiation of hPSCs to TSCs remain poorly understood. In this study, …

us, br, it (code pays fourni par la source)

Maternal distress, DNA methylation, and fetal programing of stress physiology in Brazilian mother–infant pairs

Kyle S. Wiley, Caroline Camilo, Gisele Rodrigues Gouveia, Veronica Luiza Vale Euclydes et autres

Maternal prenatal psychosocial stress is associated with adverse hypothalamic-pituitary-adrenal axis (HPAA) function among infants. Although the biological mechanisms influencing this process remain unknown, altered DNA methylation is considered to be one potential mechanism. We investigated associations between maternal prenatal psychological distress, infant …

us, br (code pays fourni par la source)