Ali Tebbi

Linear programming bounds for distributed storage codes

Ali Tebbi, Terence Chan, Chi Wan Sung

A major issue of locally repairable codes is their robustness. If a local repair group is not able to perform the repair process, this will result in increasing the repair cost. Therefore, it is critical for a locally repairable code to have …

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Multi-Rack Distributed Data Storage Networks

Ali Tebbi, Terence Chan, Chi Wan Sung

The majority of works in distributed storage networks assume a simple network model with a collection of identical storage nodes with the same communication cost between the nodes. In this paper, we consider a realistic multi-rack distributed data storage network and present …

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The P2X4 purinergic receptor regulates hepatic myofibroblast activation during liver fibrogenesis

Camille Le Guilcher, Isabelle Garcin, Olivier Dellis, Florent Cauchois et autres

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Coded caching in partially cooperative D2D communication networks

Ali Tebbi, Chi Wan Sung

The backhaul traffic is becoming a major concern in wireless and cellular networks (e.g., 4G-LTE and 5G) with the increasing demands for online video streaming. Caching the popular content in the cache memory of the network users (e.g., mobile devices) is an …

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The purinergic receptor P2X4 regulates liver fibrogenesis

Camille Le Guilcher, Isabelle Garcin, Ali Tebbi, Isabelle Doignon et autres

The P2X4 purinergic receptor impacts liver regeneration after partial hepatectomy in mice through the regulation of biliary homeostasis

Aurore Besnard, Julien Gautherot, Boris Julien, Ali Tebbi et autres

UNLABELLED: Many regulatory pathways are involved in liver regeneration after partial hepatectomy (PH), to initiate growth, protect liver cells, and sustain remnant liver functions. Extracellular adenosine triphosphate rises in blood and bile after PH and contributes to liver regeneration, although purinergic receptors …

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Deficiency of multidrug resistance 2 contributes to cell transformation through oxidative stress

Ali Tebbi, Florence Levillayer, Grégory Jouvion, Laurence Fiette et autres

Multidrug resistance 2 (Mdr2), also called adenosine triphosphate-binding cassette B4 (ABCB4), is the transporter of phosphatidylcholine (PC) at the canalicular membrane of mouse hepatocytes, which plays an essential role for bile formation. Mutations in human homologue MDR3 are associated with several liver …

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Caspase-dependent Proteolysis of Human Ribonucleotide Reductase Small Subunits R2 and p53R2 during Apoptosis

Ali Tebbi, Olivier Guittet, Karine Tuphile, Aimeric Cabrié et autres

Ribonucleotide reductase (RnR) is a key enzyme synthesizing deoxyribonucleotides for DNA replication and repair. In mammals, the R1 catalytic subunit forms an active complex with either one of the two small subunits R2 and p53R2. Expression of R2 is S phase-specific and …

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A code design framework for multi-rack distributed storage

Ali Tebbi, Terence Chan, Chi Wan Sung

In practical distributed storage networks, data centres house hundreds of racks, each of which contains several storage nodes. However, the majority of works in distributed storage assume a simple network model with a collection of identical storage nodes with same communication cost …

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Linear programming bounds for robust locally repairable storage codes

Ali Tebbi, Terence Chan, Chi Wan Sung

Locally repairable codes are used in distributed storage networks to minimise the number of survived nodes required to repair a failed node. However, the robustness of these codes is a main concern since locally repair procedure may fail when there are multiple …

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LIM-Only Protein FHL2 Activates NF-κB Signaling in the Control of Liver Regeneration and Hepatocarcinogenesis

Jennifer Dahan, Yann Nouët, Grégory Jouvion, Florence Levillayer et autres

Four-and-a-half LIM-only protein 2 (FHL2) is an important mediator in many signaling pathways. In this study, we analyzed the functions of FHL2 in nuclear factor κB (NF-κB) signaling in the liver. We show that FHL2 enhanced tumor necrosis factor (TNF) receptor-associated factor …

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Early Mitochondrial Adaptations in Skeletal Muscle to Diet-Induced Obesity Are Strain Dependent and Determine Oxidative Stress and Energy Expenditure But Not Insulin Sensitivity

Sihem Boudina, Sandra Sena, Crystal Sloan, Ali Tebbi et autres

This study sought to elucidate the relationship between skeletal muscle mitochondrial dysfunction, oxidative stress, and insulin resistance in two mouse models with differential susceptibility to diet-induced obesity. We examined the time course of mitochondrial dysfunction and insulin resistance in obesity-prone C57B and …

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