Marina Yu. Peredelskaya

Choosing an antihistamine for patients with allergic diseases

Marina Yu. Peredelskaya, Natalia M. Nenasheva, Olga A. Belik, Oksana V. Sebekina et autres

The article discusses the issues of rational choice of H1-antihistamines (H1-AHs) in the treatment of allergic diseases, mainly allergic rhinitis (AR) and urticaria. Modern ideas about the pathogenetic mechanisms of allergy are described, including the role of histamine and immunoglobulin E, as …

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Evaluation of the sensitization spectrum in patients with respiratory allergies in the Moscow region using the domestic allergy chip

Oksana V. Sebekina, Н М Ненашева, Marina Yu. Peredelskaya

BACKGROUND: The goal of an allergist is to identify a causally significant allergen in a timely manner, which allows for the administration of modern treatment for allergic diseases. To confirm sensitization, diagnostics are performed using skin tests with allergen extracts or the …

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Effects of various electronic nicotine delivery systems in asthma: a cohort study

Marina Yu. Peredelskaya, Н М Ненашева, Alexander A. Yudin, Artem N. Burtsev et autres

BACKGROUND: Electronic nicotine delivery systems (ENDS) are becoming increasingly widely available and popular as an alternative to tobacco cigarettes; therefore, it is relevant to assess their effects on the disease course and symptom control in asthma. AIM: This study aimed to assess …

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Results of a survey of high school adolescents and secondary specialized institutions on the smoking status and preferred smoking methods

Marina Yu. Peredelskaya, Natalia M. Nenasheva, Е. А. Орлова, O.A. Kulieva et autres

Adolescent smoking remains an important public health issue, as it leads to nicotine dependence and increases the risk of developing chronic diseases. Despite the availability of data on the prevalence of smoking among young people, the role of new forms of nicotine …

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Clinical efficacy and safety of fixed-dose intranasal combination of azelastine hydrochloride and fluticasone propionate for treatment of seasonal allergic rhinitis

Natalia M. Nenasheva, Oksana V. Sebekina, Marina Yu. Peredelskaya

Allergic rhinitis is a common chronic respiratory disease that affects millions of people worldwide and has a significant impact on their quality of life, productivity, and performance. Achieving control of the symptoms of moderate/severe allergic rhinitis, which often requires the use of …

Interpretation of Laboratory Studies in Allergy

T.S. Belokhvostikova, M.A. Godkov, N.M. Nenasheva Nenasheva, С. Н. Буйнова et autres

How to fit an antihistamine, taking into account the individual characteristics of the patient: From pharmacokinetics to profiling

Natalia M. Nenasheva, Oksana V. Sebekina, Marina Yu. Peredelskaya, Kristina Anatolyevna Akmalova

The authors of the article describe the dependence of the effectiveness of any drug on the "correctness" of its choice for the patient and conclude that patient profiling can serve as an effective clinical method for selecting optimal therapy. When prescribing antihistamines, …

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Is Quifenadine an antihistamine of the first generation? Do we know everything…

Dmitry Alekseevich Sychev, Natalia M. Nenasheva, Oksana V. Sebekina, Marina Yu. Peredelskaya

Quifenadine was developed in the 1970s in the laboratory of M.D. Mashkovsky and is one of the first examples of the creation of a new class of non-sedative antihistamine with polyfunctional action that combines high selective activity to block histamine receptor type …

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Treatment of patients with atopic dermatitis and extremely high immunoglobulin E: world experience and own clinical observation

Oksana V. Sebekina, Marina Yu. Peredelskaya, Natalia M. Nenasheva, Alexander A. Yudin

Atopic dermatitis is a chronic inflammatory skin disease characterized by a recurrent course, difficulty in individual selection of therapy, especially in patients with severe course. When examining and treating such patients, one of the routine diagnostic methods is to determine the level …

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The effect of the COVID-19 pandemic on severe asthma care in Europe: will care change for good?

Katrien A.B. Eger, Dóra Paróczai, Alison M. Bacon, Florence Schleich et autres

Background: The coronavirus disease 2019 (COVID-19) pandemic has put pressure on healthcare services, forcing the reorganisation of traditional care pathways. We investigated how physicians taking care of severe asthma patients in Europe reorganised care, and how these changes affected patient satisfaction, asthma …

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THE PLACE OF INHALED GLUCOCORTICOSTEROIDS IN THE TREATMENT OF PATIENTS WITH BRONCHIAL ASTHMA DURING THE COVID-19 PANDEMIC

Marina Yu. Peredelskaya, Natalia M. Nenasheva

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Selection of therapy in smoking patients with bronchial asthma

Marina Yu. Peredelskaya, Natalia M. Nenasheva, Y A Peredelskiy, Oksana V. Sebekina

Despite the evidence and logical fact that smoking and asthma are incompatible, many patients are smoke. The proportion of smokers among asthmatics is comparable to the proportion of smokers in the population. The proportion of smokers among asthmatics is comparable to the …

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