Steen Dalby Kristensen

Changes in platelet maturity and reactivity following acute ST-segment elevation myocardial infarction

Oliver Buchhave Pedersen, Peter H. Nissen, Leonardo Pasalic, Anne‐Mette Hvas et autres

Background Reduced effect of antiplatelet therapy has been reported in patients with ST-segment elevation myocardial infarction (STEMI). This could partly be explained by an increase of highly reactive immature platelets. Objectives To investigate changes in platelet maturity and reactivity after acute STEMI. …

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Comparison of Outcome After Percutaneous Coronary Intervention for De Novo and In-Stent Restenosis Indications

Lars Jakobsen, Evald Høj Christiansen, Phillip Michael Freeman, Johnny A. Kahlert et autres

In-stent restenosis (ISR) still occurs after percutaneous coronary intervention (PCI). Few studies have compared the outcomes of PCI for de novo stenosis with those of PCI for ISR, and the results are conflicting. The present study aimed to conduct this comparison. Using …

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Altered clot formation and fibrinolysis in heart transplant recipients

Karsten Bjerre, Tor Skibsted Clemmensen, Steen Hvitfeldt Poulsen, Anne‐Mette Hvas et autres

Abstract Background Long-term survival after heart transplantation (HTx) is limited by cardiac allograft vasculopathy (CAV), a frequent accelerated form of coronary artery disease. The pathogenesis remains incompletely understood, but thrombosis may be involved. We aimed to investigate clot formation and fibrinolysis in …

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Temporal trends in major bleeding after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction from 2003 to 2017: the Western Denmark Heart Registry

Pernille Gro Thrane, Kevin Kris Warnakula Olesen, Troels Thim, Christine Gyldenkerne et autres

Abstract Background Management of patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) has changed during the last two decades. Introduction of more potent platelet inhibitors may carry an increased risk of bleeding complications, while other therapeutic …

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Trends in major cardiac events after ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention from 2003 to 2017: the western Denmark heart registry

Pernille Gro Thrane, Kevin Kris Warnakula Olesen, Troels Thim, Christine Gyldenkerne et autres

Abstract Background In Denmark, primary percutaneous coronary intervention (PCI) has been the national reperfusion strategy since 2003. We recently reported a gradual decline in 1-year mortality in patients treated with pPCI-treated STEMI from 2003 to 2017. To elucidate potential causes of this …

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10-Year Mortality After ST-Segment Elevation Myocardial Infarction Compared to the General Population

Pernille Gro Thrane, Kevin Kris Warnakula Olesen, Troels Thim, Christine Gyldenkerne et autres

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Diabetes and coronary artery disease as risk factors for dementia

Kevin Kris Warnakula Olesen, Pernille Gro Thrane, Christine Gyldenkerne, Reimar Wernich Thomsen et autres

AIMS: Diabetes is associated with an increased risk of dementia, but it is still debated to which degree this risk depends on the presence of atherosclerotic cardiovascular disease (CVD). In this study, we hypothesize that patients with diabetes and coexisting coronary artery …

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Acute and subacute effects of strenuous exercise on platelet aggregation, coagulation and fibrinolysis in patients with stable coronary artery disease

Jacobina Kristiansen, Erik Lerkevang Grove, Tórur Sjúrðarson, Magni Mohr et autres

INTRODUCTION: Strenuous exercise may occasionally cause coronary thrombosis with myocardial infarction and sudden cardiac death. MATERIALS AND METHODS: Patients with stable coronary artery disease (CAD) (n = 164) and healthy individuals (n = 25) performed strenuous exercise on a bicycle ergometer. Blood …

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A systems approach to hazard identification for solar-powered and wave-propelled unmanned surface vehicle

Steen Dalby Kristensen, Alberto Dallolio, Ingrid Bouwer Utne

A systems approach to

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Long‐term outcomes after coronary intervention with biodegradable polymer stents in patients with acute coronary syndromes

Manijeh Noori, Evald Høj Christiansen, Bent Raungaard, Anders Junker et autres

BACKGROUND: Patients with acute coronary syndromes (ACS) may have worse outcomes after percutaneous coronary intervention compared to patients without ACS. AIMS: To compare 5-year efficacy and safety outcomes in patients with and without ACS treated with biodegradable polymers, the ultrathin strut sirolimus-eluting …

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Research Priorities in Critical Care Cardiology

Paul Elliott Miller, Kurt Huber, Erin Ann Bohula, Konstantin Alexander Krychtiuk et autres

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Life expectancy in women and men after STEMI: a comparison to a matched general population

Pernille Gro Thrane, Kevin Kris Warnakula Olesen, Christine Gyldenkerne, M K Hansen et autres

Abstract Background/Introduction ST-elevation myocardial infarction (STEMI) is considered a risk factor for short- and long-term mortality. Further, studies indicate that female sex is associated with increased mortality among STEMI patients. Our aim was to assess the impact of female and male sex …

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