Hugo Carignano

Differential protein abundance in colostrum-derived extracellular vesicles from bovine leukemia virus-infected cattle are implicated in immune regulation and inflammation

Cecilia Valeria Perez, Hugo Carignano, Yamila Celeste Marchetti, Diego D. González et autres

Introduction: Bovine leukemia virus (BLV) is an oncogenic retrovirus that naturally infects cattle. Once infected, the virus persists indefinitely throughout life at a transcriptionally silent stage. Soon after infection, humoral and cytotoxic activities efficiently abolish the viral replicative cycle, allowing only mitotic …

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Co-expression of bovine leukemia virus and bovine foamy virus-derived miRNAs in naturally infected cattle

Marcos Petersen, Guillermo Suárez Archilla, Cecilia Valeria Perez, Diego D. González et autres

ABSTRACT Among the viruses that encode microRNAs (miRNAs) and infect cattle, such as bovine leukemia virus (BLV), bovine foamy virus (BFV), and Bovine herpesviruses, BLV has gained attention due to the critical role that BLV-miRNAs play in inducing lymphosarcoma in infected animals. …

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Humoral and cell-mediated immune response against the Mce2B (Rv0590/Mb0605) cell-wall protein of Mycobacterium bovis

Ximena Ferrara Muñiz, Micaela Encinas, Wanderson Marques da Silva, Sergio Garbaccio et autres

ar (code pays fourni par la source)

Whole-transcriptome analysis of BLV-infected cows reveals downregulation of immune response genes in high proviral loads cows

Marcos Petersen, Guillermo Suárez Archilla, Marcos Miretti, Karina Trono et autres

Bovine leukemia virus (BLV) is a retrovirus that infects cattle, causing bovine enzootic leukosis, a chronic disease characterized by the proliferation of infected B cells. BLV proviral load (PVL) is a key determinant of disease progression and transmission risk. Cattle can exhibit …

ar (code pays fourni par la source)

Co-expression of Bovine leukemia virus and Bovine foamy virus-derived miRNAs in naturally infected cattle

Marcos Petersen, Guillermo Suárez Archilla, Cecilia Valeria Perez, Diego D. González et autres

Abstract Among the viruses that encode miRNAs and infect cattle such as Bovine leukemia virus (BLV), Bovine foamy virus (BFV) and Bovine herpesviruses (BoHV), BLV has gained attention due to the critical role that BLV-miRNAs may play in inducing lymphosarcoma in infected …

ar, br, ec, uy (code pays fourni par la source)

Performance of the PhoP (Rv0757/Mb0780) protein as diagnostic antigen for bovine tuberculosis

Ximena Ferrara Muñiz, Wanderson Marques da Silva, Sergio Garbaccio, Carlos Javier Garro et autres

ar (code pays fourni par la source)

Whole-transcriptome analysis of BLV-infected cows reveals downregulation of immune response genes in high proviral loads cows

Marcos Petersen, Guillermo Suárez Archilla, Marcos Miretti, Karina Trono et autres

Abstract Bovine leukemia virus (BLV) is a retrovirus that infects cattle, causing bovine enzootic leukosis, a chronic disease characterized by the proliferation of infected B cells. BLV proviral load (PVL) is a key determinant of disease progression and transmission risk. Cattle can …

ar, br, ec (code pays fourni par la source)

Effects of breed and genomic inbreeding on milk, fat and protein lactation yields and fertility traits in pasture-based dairy cows in Argentina

María José Beribe, Hugo Carignano, Mario Andrés Poli, N. López‐Villalobos

Abstract The objective of the current study was to evaluate the effects of breed and genomic inbreeding on 305-day lactation yields of milk, fat and protein; and fertility traits of pasture-based dairy cows in Argentina. The genomic inbreeding and heterozygosity of 890 …

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Complete genome sequence of deformed wing virus and black queen cell virus isolated from honeybees ( Apis mellifera ) in Argentina

Fernanda N. Gonzalez, Cecilia Ferrufino, María José Dus Santos, Hugo Carignano

We report the complete genome sequence of deformed wing virus and black queen cell virus isolated from Argentinean's honeybees. These sequence data will be valuable for future research on the viral variants present in the country and the development of strategies to …

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Bovine leukemia virus encoded blv-miR-b4-3p microRNA is associated with reduced expression of anti-oncogenic gene in vivo

Marcos Petersen, Hugo Carignano, Claudia Mongini, Diego D. González et autres

Bovine leukemia virus (BLV) is a retrovirus that causes malignant B-cell lymphoma in up to ten-percent of infected cattle. To date, the mechanisms of BLV linked to malignant transformation remain elusive. Although BLV-encoded miRNAs have been associated with the regulation of different …

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Unveiling the Biosynthetic Pathway for Short Mycolic Acids in Nontuberculous Mycobacteria: Mycobacterium smegmatis MSMEG_4301 and Its Ortholog Mycobacterium abscessus MAB_1915 Are Essential for the Synthesis of α′-Mycolic Acids

Cecilia Beatriz Di Capua, Juan M. Belardinelli, Hugo Carignano, María V. Buchieri et autres

Mycobacterium abscessus is a nontuberculous mycobacterium responsible for an increasing number of hard-to-treat infections due to the impervious nature of its cell envelope, a natural barrier to several antibiotics. Mycolic acids are key components of that envelope; thus, their synthesis is a …

ar (code pays fourni par la source)

Towards inclusive funding practices for early career researchers

Charlotte M. de Winde, Sarvenaz Sarabipour, Hugo Carignano, Sejal Davla et autres

Securing research funding is a challenge faced by most scientists in academic institutions worldwide. Funding success rates for all career stages are low, but the burden falls most heavily on early career researchers (ECRs). These are young investigators in training and new …

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