Nuno Henrique Franco

Finding a place for new approach methodologies (NAMs) in biomedical research

Alexandra Schaffert, Arti Devi Ahluwalia, Jeffrey John Bajramovic, Nuno Henrique Franco et autres

New approach methodologies (NAMs) can greatly contribute to the replacement and reduction of animal experiments in biomedical science. However, while NAMs have seen considerable investment and adoption in toxicology, this growth has not found a parallel in basic and translational biomedical research. …

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On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo et autres

A review of behavioural studies using home-cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the …

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Building bridges: Involvement of animal care staff and laboratory technicians in experimental planning and conduct of animal studies for better job satisfaction and science

Fernando Gonzalez-Uarquin, Paulin Jirkof, Bettina Bert, Penny Hawkins et autres

The involvement of non-scientific staff in discussions about animal welfare and scientific quality is essential for biomedical research progress. In this study, we developed a survey to collect the self-perception of animal care staff (ACS) and laboratory technicians about their involvement in …

A call for preregistration of in vitro research

Céline Heinl, Nuno Henrique Franco, Bettina Bert, Katherina Siewert et autres

This article highlights the benefits of preregistration in improving the reliability and transparency of in vitro studies. By preregistering their studies, researchers can make their findings more reproducible, paving the way for medical progress, and accelerating the replacement of animal experiments.

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Building bridges: Involvement of animal care staff and laboratory technicians in experimental planning and conduct of animal studies for better job satisfaction and science

Fernando Gonzalez-Uarquin, Paulin Jirkof, Bettina Bert, Penny Hawkins et autres

The involvement of non-scientific staff in discussions about animal welfare and scientific quality is essential for biomedical research progress. In this study, we developed a survey to collect the self-perception of animal care staff (ACS) and laboratory technicians about their involvement in …

de, ch, gb, mk, tr, pt, co, ee, at, no, fr, it (code pays fourni par la source)

Education and Training School in Home Cage Monitoring: The ‘Whys’ and ‘Hows’

Nuno Henrique Franco, Silvia Mandillo, Lior Bikovski

Abstract The adoption of Home Cage Monitoring (HCM) systems, as well as its effective and ethical use, requires proper education and training in this technology. This chapter explores the critical role of training in preparing researchers to handle the complexities associated with …

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ETPLAS Conference: Shaping the future of LAS education and training

Ana Isabel Santos, Nuno Henrique Franco

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The veterinary surgeon as a researcher – two conflicting hats?

Nuno Henrique Franco, Manuel Magalhães Sant'Ana

THE DILEMMAYou are the sole named veterinary surgeon (NVS) at a small research facility in the UK.In addition to your duties, you are pursuing a PhD with a project on laboratory animal welfare involving collecting additional data non-invasively from another licenced project …

The 2025 FELASA Congress in Athens: From Aristotle to AI

Nuno Henrique Franco, Otto Kalliokoski, Vootele Võikar

The 16th FELASA Congress took place June 2025 in the cradle of science, Athens. Upon arrival, more than 2,000 professionals from 52 countries were welcomed by “Aristotle the Octopus”, a mascot alluding to Greek scientific heritage, Aristotle’s pioneering zoological observations and the …

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Finding a Place for New Approach Methodologies (NAMs) in Biomedical Research

Alexandra Schaffert, Arti Devi Ahluwalia, Jeffrey John Bajramovic, Nuno Henrique Franco et autres

New Approach Methodologies (NAMs) can greatly contribute to the Replacement and Reduction of animal experiments in biomedical science. However, while NAMs have seen considerable investment and adoption in toxicology, this growth has not found a parallel in basic and translational biomedical research. …

fi, it, nl, pt, at, no (code pays fourni par la source)

Teaching experimental design: outputs from the FELASA Working Group

Derek Fry, Manuel Berdoy, Monica Forni, Carlos Óscar S. Sorzano et autres

research studies. We present here outputs from the FELASA Experimental Design Working Group, set up to consider the current provision of ED teaching and how it might be improved and harmonised across the laboratory animal science community. It is hoped that these …

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Contactless body temperature assessment for signalling humane endpoints in a mouse model of sepsis

Carlos Ramón Ruiz Miranda, Liliana Oliveira, Alexandre Medeiros do Carmo, I. Anna S. Olsson et autres

Abstract Minimising suffering is an ethical and legal requirement in animal research. This is particularly relevant for research on animal models of sepsis and septic shock, which show rapid progression towards severe stages and death. Specific and reliable criteria signalling non-recovery points …

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