Bernard Mazoyer

Profiling brain morphology for autism spectrum disorder with two cross-culture large-scale consortia

Xue-Ru Fan, Ye He, Yin-Shan Wang, Lei Li et autres

We explore neurodevelopmental heterogeneity in Autism Spectrum Disorder (ASD) through normative modeling of cross-cultural cohorts. By leveraging large-scale datasets from Autism Brain Imaging Data Exchange (ABIDE) and China Autism Brain Imaging Consortium (CABIC), our model identifies two ASD subgroups with distinct brain …

cn, au, gb, us, ca, cu, kr, in, de, fr, sg, ie, cl, Afrique du Sud, se, br, fi, jp (code pays fourni par la source)

Genetic variants for head size share genes and pathways with cancer

Alexander Teumer, Vince D. Calhoun, Manabu Nagata, Raymond A. Poot et autres

us (code pays fourni par la source)

Genetic variants for head size share genes and pathways with cancer

Maria J. Knol, Raymond A. Poot, Tavia E. Evans, Claudia L. Satizábal et autres

The size of the human head is highly heritable, but genetic drivers of its variation within the general population remain unmapped. We perform a genome-wide association study on head size (N = 80,890) and identify 67 genetic loci, of which 50 are …

nl, us, fr, de, ch, gb, pl, ca, no, se, hk, au, sg, fi, jp, at (code pays fourni par la source)

Atypical Brain Aging and Its Association With Working Memory Performance in Major Depressive Disorder

Natalie C. W. Ho, Richard A. I. Bethlehem, Jakob Seidlitz, Nikita Nogovitsyn et autres

ca, gb, us (code pays fourni par la source)

A longitudinal resource for population neuroscience of school-age children and adolescents in China

Xue-Ru Fan, Yinshan Wang, Da Chang, Ning Yang et autres

During the past decade, cognitive neuroscience has been calling for population diversity to address the challenge of validity and generalizability, ushering in a new era of population neuroscience. The developing Chinese Color Nest Project (devCCNP, 2013-2022), the first ten-year stage of the …

cn, us, au, gb, ca, cu, in, de, kr, fr, sg (code pays fourni par la source)

Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease

Marie‐Gabrielle Duperron, Maria J. Knol, Quentin Le Grand, Tavia E. Evans et autres

Perivascular space (PVS) burden is an emerging, poorly understood, magnetic resonance imaging marker of cerebral small vessel disease, a leading cause of stroke and dementia. Genome-wide association studies in up to 40,095 participants (18 population-based cohorts, 66.3 ± 8.6 yr, 96.9% European …

fr, nl, jp, us, de, gb, at, ca, es, sg, au, cn, cl (code pays fourni par la source)

Normative Modeling of Brain Morphometry Across the Lifespan Using CentileBrain: Algorithm Benchmarking and Model Optimization

Ruiyang Ge, Yuetong Yu, Yi Xuan Qi, Yunan Vera Fan et autres

We present an empirically benchmarked framework for sex-specific normative modeling of brain morphometry that can inform about the biological and behavioral significance of deviations from typical age-related neuroanatomical changes and support future study designs. This framework was developed using regional morphometric data …

ca, us, no, se, gb, es, it, de, nl, ch, au, ie, fr, Afrique du Sud, ru, jp, cn, sg (code pays fourni par la source)

Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease

Marie‐Gabrielle Duperron, Maria J. Knol, Quentin Le Grand, Tavia E. Evans et autres

Abstract Background Perivascular space (PVS) burden is an emerging MRI‐marker of cerebral small vessel disease (cSVD), a leading cause of stroke and dementia. Underlying mechanisms of PVS are unknown. PVS are thought to be related to the glymphatic system, involved in brain …

fr, nl, jp, us, de, gb, at, ca, es, sg, au (code pays fourni par la source)

Publisher Correction: Brain charts for the human lifespan

Richard A. I. Bethlehem, Jakob Seidlitz, Simon R. White, Jacob W. Vogel et autres

Author notes These authors contributed equally: R. A. I. Bethlehem, J. Seidlitz, S. R. White These authors jointly supervised this work: E. T. Bullmore, A. F. Alexander-Bloch Authors and Affiliations Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK R. …

gb, us, au, ca, cn, cu, kr, in, de, fr, sg, ie, cl, Afrique du Sud, se, br, fi, jp (code pays fourni par la source)

Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life Stages

Amirhossein Modabbernia, Didac Vidal‐Piñeiro, Ingrid Agartz, Ole A. Andreassen et autres

us, no, es, nl, au, gb, fr, ca, de, do, se (code pays fourni par la source)

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Céline Bellenguez, Fahri Küçükali, Iris E. Jansen, Luca Kleineidam et autres

Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. …

fr, be, nl, de, es, gb, us, br, fi, se, no, au, gr, it, bg, ar, nz, ch (code pays fourni par la source)

Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life Stages

Amirhossein Modabbernia, Didac Vidal‐Piñeiro, Ingrid Agartz, Ole A. Andreassen et autres

Abstract Mechanisms underpinning age-related variations in cortical thickness in the human brain remain poorly understood. We investigated whether inter-regional age-related variations in cortical thinning (in a multicohort neuroimaging dataset from the ENIGMA Lifespan Working Group totalling 14,248 individuals, aged 4-89 years) depended …

us, no, se, es, it, nl, au, gb, ca, fr, de, cn (code pays fourni par la source)