Yong Tang

Gallic acid potentiates the anticancer efficacy of cisplatin in ovarian cancer cells through modulation of the PI3K/AKT/mTOR and CXCL12/CXCR4 signaling pathways

Jinlan Liang, Tingting Lu, Tao Shan, Wenjie Wang et autres

Background: This study investigates the antitumor effects of gallic acid (GA) on ovarian cancer cells and its potential synergistic therapeutic effects with cisplatin (DDP) through modulation of the PI3K/AKT/mTOR signaling pathway. Methods: Systematic evaluations were conducted using both in vitro cell experiments …

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Prognostic Predictive Role of Short-Term Efficacy Indicators in Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer

Ning Wang, Tingting Xu, Hong Ma, Han Li et autres

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Abstract P4-12-29: ETX-197/BG-68501, a potential best-in-class potent, selective, oral, small molecule CDK2 inhibitor, has anti-tumor activity in cancer models with Cyclin E amplification or deficiency in the Retinoblastoma 1 gene

Daliya Banerjee, Alexandra S. Weinheimer, Jingyan Gao, Fei Pang et autres

Abstract In a normal cell cycle, there is redundancy in the role of the cell-cycle dependent kinases (CDKs) in regulating G1/S phase transition. In cancer cells, the regulation of G1/S transition can be subverted by (a) amplification and elevated expression of Cyclin …

Research on Distributed Generation Access to Distribution Network for Siting and Capacity Determination and Reactive Power Optimization

Yong Tang, Yan Han, Weihong Zhang, Di Jin et autres

In order to carry out the optimal allocation of distributed generation in the distribution network, this paper proposes a single-objective particle swarm optimization algorithm combining improved inertia weights and small habitat technology, constructs a multi-objective function of weights in terms of network …

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Perioperative SARS-CoV-2 infection and postoperative complications: a single-centre retrospective cohort study in China

Fei Zhong, Jue Ma, Chang Lu, Yu Qing Zhang et autres

OBJECTIVE: To explore the association between perioperative SARS-CoV-2 infection and the postoperative complications during the breakout of the Omicron epidemic wave. DESIGN: Observational retrospective cohort study. Multivariable logistic regression was performed to explore the association between the duration from surgery to COVID-19 …

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A predictive model for the transformation from cervical inflammation to cancer based on tumor immune-related factors

Wenjie Wang, Shuang Bi, Songlin Li, Tingting Lu et autres

Introduction: Persistent high-risk human papillomavirus (HR-HPV) infection is crucial in transforming cervical intraepithelial neoplasia (CIN) into cervical cancer (CC) by evading immune responses. Additionally, changes in the tumor immune microenvironment (TIME) are increasingly linked to CIN progression to CC. Methods: In this …

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L-arabinose alleviates constipation through gastrointestinal peptide，gut microbiota，and Phlpp2 of gastrointestinal rhythms in rats

Ting Gong, Linzheng Liao, Yong Tang, Weiwei Liu et autres

Constipation is a common gastrointestinal disorder, and while L-arabinose has been shown to relieve it, the exact molecular mechanisms remain unclear. This study investigated the effects of L-arabinose in constipated rat at doses of 400, 600, and 800 mg/kg body weight (B.W.). …

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759P Efficacy and safety of HLX07 monotherapy in advanced cutaneous squamous cell carcinoma: An open-label, multicentre phase II study

Chuang Li, Ding Liang Zhu, Y. Chen, Yan Li et autres

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Patient-reported respiratory symptoms and relevant factors in patients with pulmonary nodules

Weitao Zhuang, Haijie Xu, Junhan Wu, Zijie Li et autres

Background: Pulmonary nodules (PNs) are commonly considered too small to cause respiratory symptoms. However, many PN patients present with respiratory symptoms of unknown origin. This study aims to explore these symptoms and identify the associated factors. Methods: Demographic and clinical information were …

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Laparoscopic simultaneous anterograde inguinal and pelvic lymphadenectomy for penile cancer: two planses, three holes, and six steps

Xianlin Yi, Xiu-ning Li, Yu-lei Lu, Haoyuan Lu et autres

Objective: To assess the feasibility, safety, and efficiency of simultaneous anterograde video laparoscopic inguinal and pelvic lymphadenectomy for penile cancer. Materials and methods: We reviewed retrospectively the records of 22 patients (44 lateral) who underwent inguinal lymph nodes dissection for penile cancer. …

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3D printing sequentially strengthening high-strength natural polymer hydrogel bilayer scaffold for cornea regeneration

Xiongfeng Nie, Yong Tang, Tengling Wu, Xinrui Zhao et autres

Abstract 3D printing of high-strength natural polymer biodegradable hydrogel scaffolds simultaneously resembling the biomechanics of corneal tissue and facilitating tissue regeneration remains a huge challenge due to the inherent brittleness of natural polymer hydrogels and the demanding requirements of printing. Herein, concentrated …

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The efficacy of mindfulness-based interventions on mental health among university students: a systematic review and meta-analysis

Xinyi Zuo, Yong Tang, Yifang Chen, Zhimiao Zhou

Introduction We aimed to estimate the effect of mindfulness therapy on mental health. Methods Two researchers searched 12 databases to identify relevant trials that were published from 1 January 2018 to 1 May 2023. We performed a meta-analysis to determine the effect …

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