J. Ling

Drug-drug interaction profile of sofosbuvir/velpatasvir/ voxilaprevir fixed-dose combination

Kelli L. Garrison, Beth J. Kirby, Luisa M. Stamm, Guo Ma et autres

Drug-Drug Interaction Profile of Sofosbuvir/Velpatasvir Fixed-Dose Combination

Erik Mogalian, J. McNally, Gong Shen, Lisa Moorehead et autres

Remote pharmacological post‐conditioning by intrathecal morphine: cardiac protection from spinal opioid receptor activation

J. Ling, Gordon Tin Chun Wong, Yao Lu, Zhengyuan Xia et autres

BACKGROUND: Intrathecal morphine pre-conditioning attenuates cardiac ischemia-reperfusion injury via activation of central opioid receptors. We hypothesized that intrathecal morphine also post-conditions the myocardium in the rat. METHODS: Intrathecal morphine at 0.3 μg/kg (LMPC), 3 μg/kg (MMPC) or 30 μg/kg (HMPC) was administered …

hk (code pays fourni par la source)

Activation of Central Opioid Receptors Induces Cardioprotection Against Ischemia-Reperfusion Injury

Gordon Tin Chun Wong, J. Ling, Michael G. Irwin

BACKGROUND: Small doses of intrathecal morphine provide cardioprotection similar to that conferred by IV morphine and ischemic preconditioning (IPC). We investigated the relative role of central versus peripheral opioid receptors in intrathecal morphine preconditioning (ITMPC). METHODS: Forty-eight anesthetized, open-chest, male Sprague-Dawley rats …

gb, hk, cn (code pays fourni par la source)

Monitoring whole blood concentration of tacrolimus in 1190 samples from liver transplant recipients by ELISA

Xia Dong-ya, Tao Guo, J. Ling

AIM: To monitor the concentration of tacrolimus in whole blood in liver transplant recipients and establish an optimal therapeutic window of tacrolimus, in order to provide information for rational usage in clinic. METHODS: The whole blood concentrations of tacrolimus were measured by …

cn (code pays fourni par la source)